» Articles » PMID: 20954277

Diagnosis and Management of Angioedema with Abdominal Involvement: a Gastroenterology Perspective

Overview
Specialty Gastroenterology
Date 2010 Oct 19
PMID 20954277
Citations 14
Authors
Affiliations
Soon will be listed here.
Abstract

Abdominal involvement in angioedema is often a challenge to diagnose. Acute onset abdominal pain is its most common presenting symptom, and misdiagnosis may lead to unnecessary surgical intervention. Familiarity with the types and presentations of angioedema can be invaluable to clinicians as they consider the differential diagnoses of a patient presenting with abdominal pain. Detailed personal and family histories, careful physical examination of the patient, combined with knowledge of angioedema types, can help clinicians perform their diagnostic evaluation. An accurate diagnosis is essential in order to provide appropriate treatment to patients with angioedema. Depending upon the diagnosis, treatment may be the avoidance of provoking factors (such as allergens or medications), inhibiting histamine-provoked reactions, or treating C1 esterase inhibitor deficiency.

Citing Articles

Recurrent Intestinal Angioedema with Normal C1-Inhibitor: A Case Report.

Jevtic D, Taylor A, Dumic I, Sviggum E, Nordstrom C, Antic M Medicina (Kaunas). 2025; 61(2).

PMID: 40005362 PMC: 11857147. DOI: 10.3390/medicina61020245.


Intestinal Angioedema: A Mimic of an Acute Abdomen.

Pal 3rd N, Fernandes Y Cureus. 2023; 15(2):e34619.

PMID: 36891016 PMC: 9986968. DOI: 10.7759/cureus.34619.


A Case of Duodenal Edema-related Undiagnosed Hereditary Angioedema.

Kawara F, Matsuura T, Yamanaka K, Nishioka C Intern Med. 2022; 62(15):2285-2286.

PMID: 36418101 PMC: 10465281. DOI: 10.2169/internalmedicine.0869-22.


Abdominal and pelvic imaging in the diagnosis of acute abdominal attacks in patients with hereditary angioedema due to C1-inhibitor deficiency.

Obtulowicz P, Stobiecki M, Dyga W, Juchacz A, Popiela T, Obtulowicz K Postepy Dermatol Alergol. 2022; 39(4):749-756.

PMID: 36090726 PMC: 9454366. DOI: 10.5114/ada.2021.108438.


Acute Right Ventricular Dysfunction Secondary to Hereditary Angioedema Exacerbation.

Shahmohammadi A, Burtson K Cureus. 2021; 13(5):e15336.

PMID: 34235015 PMC: 8241184. DOI: 10.7759/cureus.15336.


References
1.
Frank M, Gelfand J, Atkinson J . Hereditary angioedema: the clinical syndrome and its management. Ann Intern Med. 1976; 84(5):580-93. DOI: 10.7326/0003-4819-84-5-580. View

2.
Bowen T, Cicardi M, Bork K, Zuraw B, Frank M, Ritchie B . Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Ann Allergy Asthma Immunol. 2008; 100(1 Suppl 2):S30-40. DOI: 10.1016/s1081-1206(10)60584-4. View

3.
Kaplan A, Greaves M . Angioedema. J Am Acad Dermatol. 2005; 53(3):373-88. DOI: 10.1016/j.jaad.2004.09.032. View

4.
Bouillet L, Longhurst H, Boccon-Gibod I, Bork K, Bucher C, Bygum A . Disease expression in women with hereditary angioedema. Am J Obstet Gynecol. 2008; 199(5):484.e1-4. DOI: 10.1016/j.ajog.2008.04.034. View

5.
Bork K, Bygum A, Hardt J . Benefits and risks of danazol in hereditary angioedema: a long-term survey of 118 patients. Ann Allergy Asthma Immunol. 2008; 100(2):153-61. DOI: 10.1016/S1081-1206(10)60424-3. View