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Histoplasma Capsulatum Prosthetic Valve Endocarditis with Negative Fungal Blood Cultures and Negative Histoplasma Antigen Assay in an Immunocompetent Patient

Overview
Journal J Clin Microbiol
Specialty Microbiology
Date 2010 Oct 8
PMID 20926709
Citations 5
Authors
Sadao Jinno
Barbara M Gripshover
Tracy L Lemonovich
James M Anderson
Michael R Jacobs
Affiliations
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Abstract

We report a case of Histoplasma capsulatum endocarditis in which Histoplasma antigen assay and fungal blood cultures were negative. The diagnosis was made by microscopic examination and culture of the excised valve. Histoplasma capsulatum should be considered in the differential diagnosis of culture-negative endocarditis in regions where it is endemic and in travelers.

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References
1.
Kauffman C . Histoplasmosis: a clinical and laboratory update. Clin Microbiol Rev. 2007; 20(1):115-32. PMC: 1797635. DOI: 10.1128/CMR.00027-06. View
2.
Boland J, Chung H, Robberts F, Wilson W, Steckelberg J, Baddour L . Fungal prosthetic valve endocarditis: Mayo Clinic experience with a clinicopathological analysis. Mycoses. 2010; 54(4):354-60. DOI: 10.1111/j.1439-0507.2010.01884.x. View
3.
Connolly P, Durkin M, LeMonte A, Hackett E, Wheat L . Detection of histoplasma antigen by a quantitative enzyme immunoassay. Clin Vaccine Immunol. 2007; 14(12):1587-91. PMC: 2168386. DOI: 10.1128/CVI.00071-07. View
4.
Fournier P, Thuny F, Richet H, Lepidi H, Casalta J, Arzouni J . Comprehensive diagnostic strategy for blood culture-negative endocarditis: a prospective study of 819 new cases. Clin Infect Dis. 2010; 51(2):131-40. DOI: 10.1086/653675. View
5.
Chemaly R, Tomford J, Hall G, Sholtis M, Chua J, Procop G . Rapid diagnosis of Histoplasma capsulatum endocarditis using the AccuProbe on an excised valve. J Clin Microbiol. 2001; 39(7):2640-1. PMC: 88199. DOI: 10.1128/JCM.39.7.2640-2641.2001. View