Experimental Design Based 3-D QSAR Analysis of Steroid-protein Interactions: Application to Human CBG Complexes

Overview

Journal J Comput Aided Mol Des

Publisher Springer

Specialties Biomedical Engineering
Molecular Biology

Date 1990 Dec 1

PMID 2092083

Citations 7

Authors

U Norinder

Affiliations

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Abstract

An experimental design based 3-D QSAR analysis using a combination of principal component and PLS analysis is presented and applied to human corticosteroid-binding globulin complexes. The predictive capability of the created model is good. The technique can also be used as guidance when selecting new compounds to be investigated.

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References

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