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Human Echinococcosis: a Neglected Disease

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Publisher Wiley
Specialty Gastroenterology
Date 2010 Sep 24
PMID 20862339
Citations 45
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Abstract

Echinococcosis is among the most neglected parasitic diseases. Development of new drugs and other treatment modalities receives very little attention, if any. In most developed countries, Cystic Echinococcosis (CE) is an imported disease of very low incidence and prevalence and is found almost exclusively in migrants from endemic regions. In endemic regions, predominantly settings with limited resources, patient numbers are high. Whole communities do not have access to appropriate treatment. The choice of treatment modalities is limited because of poor infrastructure and shortage of equipment and drugs. In this context, CE meets the criteria for a neglected disease. Furthermore, the terminology related to the designations around the parasite, its evolution and some therapeutic procedures is not uniform and sometimes inappropriate terms and wrong designations are used based on incorrect concepts. Although all of us know the different aspects of the disease it is pertinent to remember some important points and, above all, to clarify some aspects concerning the hydatid cyst's nomenclature in order to understand better the therapeutic options in the liver locations, particularly the different surgical approaches.

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References
1.
Saimot A . Medical treatment of liver hydatidosis. World J Surg. 2001; 25(1):15-20. DOI: 10.1007/s002680020003. View

2.
Keshmiri M, Baharvahdat H, Fattahi S, Davachi B, Dabiri R, Baradaran H . Albendazole versus placebo in treatment of echinococcosis. Trans R Soc Trop Med Hyg. 2001; 95(2):190-4. DOI: 10.1016/s0035-9203(01)90162-2. View

3.
Magistrelli P, Masetti R, Coppola R, Messia A, Nuzzo G, Picciocchi A . Surgical treatment of hydatid disease of the liver. A 20-year experience. Arch Surg. 1991; 126(4):518-22; discussion 523. DOI: 10.1001/archsurg.1991.01410280122020. View

4.
Horton R . Albendazole in treatment of human cystic echinococcosis: 12 years of experience. Acta Trop. 1997; 64(1-2):79-93. DOI: 10.1016/s0001-706x(96)00640-7. View

5.
Menezes da Silva A . Hydatid cyst of the liver-criteria for the selection of appropriate treatment. Acta Trop. 2003; 85(2):237-42. DOI: 10.1016/s0001-706x(02)00271-1. View