Analysis of Cardiac Autonomic Modulation in Obese and Eutrophic Children

Overview

Journal Clinics (Sao Paulo)

Publisher Elsevier

Specialty General Medicine

Date 2010 Sep 14

PMID 20835556

Citations 31

Authors

Luiz Carlos Marques Vanderlei

Carlos Marcelo Pastre

Ismael Forte Freitas Junior

Moacir Fernandes de Godoy

Affiliations

Soon will be listed here.

Abstract

Introduction: Obesity causes alterations in cardiac autonomic function. However, there are scarce and conflicting data on this function with regard to heart rate variability in obese children.

Objective: To compare the autonomic function of obese and eutrophic children by analyzing heart rate variability.

Methods: One hundred twenty-one children (57 male and 64 female) aged 8 to 12 years were distributed into two groups based on nutritional status [obese (n = 56) and eutrophic (ideal weight range; n = 65) according to the body mass index reference for gender and age]. For the analysis of heart rate variability, heart rates were recorded beat by beat as the children rested in the dorsal (prone) position for 20 minutes. Heart rate variability analysis was carried out using linear approaches in the domains of frequency and time. Either Student's t-test or the Mann-Whitney U-test was applied to compare variables between groups. Statistical significance was set at 5%.

Results: The SDNN, RMSSD, pNN50, SD1, SD2, LF and HF indices in milliseconds squared were lower among the obese children when compared to the eutrophic group. There were no alterations in the SD1/SD2 ratio, LF/HF ratio, LF index or HF index in normalized units. There was a significant difference between groups in the RR interval (R-to-R EKG interval).

Conclusion: The obese children exhibited modifications in heart rate variability, characterized by a reduction in both sympathetic and parasympathetic activity. These findings stress the need for the early holistic care of obese children to avoid future complications.

Citing Articles

Autonomic Function in Obese Children and Adolescents: Systematic Review and Meta-Analysis.

Papadopoulos G, Balomenou F, Sakellariou X, Tassopoulos C, Nikas D, Giapros V J Clin Med. 2024; 13(7).

PMID: 38610619 PMC: 11012290. DOI: 10.3390/jcm13071854.

Influence of physical fitness and weight status on autonomic cardiac modulation in children.

Latorre-Roman P, DE LA Casa Perez A, Pancorbo-Serrano D, Consuegra-Gonzalez P, Salas-Sanchez J, Munoz-Jimenez M Pediatr Res. 2023; 94(5):1754-1763.

PMID: 37280325 DOI: 10.1038/s41390-023-02676-1.

Central markers of obesity affect heart rate variability independent of physical activity in young adults.

Banerjee A, Singh N, Raju A, Gupta R J Family Med Prim Care. 2022; 11(6):2521-2525.

PMID: 36119331 PMC: 9480774. DOI: 10.4103/jfmpc.jfmpc_1970_21.

Anthropometric Determinants of Respiratory Sinus Arrhythmia in Children.

Lubocka P, Sabiniewicz R, Suligowska K, Zdrojewski T Int J Environ Res Public Health. 2022; 19(1).

PMID: 35010824 PMC: 8744931. DOI: 10.3390/ijerph19010566.

Relationship between heart rate variability and body mass index: A cross-sectional study of preschool children.

Speer K, Koenig J, Telford R, Olive L, Mara J, Semple S Prev Med Rep. 2022; 24:101638.

PMID: 34976689 PMC: 8684011. DOI: 10.1016/j.pmedr.2021.101638.

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