[Postoperative Wound Infections. Pathophysiology, Risk Factors and Preventive Concepts]

Overview

Journal Anaesthesist

Specialty Anesthesiology

Date 2010 Sep 11

PMID 20830460

Citations 10

Authors

T Hachenberg

M Senturk

O Jannasch

H Lippert

Affiliations

Soon will be listed here.

Abstract

Postoperative wound infections are the third most common type of nosocomial infection in German emergency hospitals after pneumonia and urinary infections. They are associated with increased morbidity and mortality, prolonged hospital stay and increased costs. The most important risk factors include the microbiological state of the skin surrounding the incision, delayed or premature prophylaxis with antibiotics, duration of surgery, emergency surgery, poorly controlled diabetes mellitus, malignant disease, smoking and advanced age. Anesthesiological measures to decrease the incidence of wound infections are maintaining normothermia, strict indications for allogenic blood transfusions and timely prophylaxis with antibiotics. Blood glucose concentrations should be kept in the range of 8.3-10 mmol/l (150-180 mg/dl) as lower values are associated with increased complications. Intraoperative and postoperative hyperoxia with 80% O(2) has not been shown to effectively decrease wound infections. The application of local anesthetics into the surgical wound in clinically relevant doses for postoperative analgesia does not impair wound healing.

Citing Articles

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Antimicrobials cetylpyridinium-chloride and miramistin demonstrate non-inferiority and no "protein-error" compared to established wound care antiseptics .

Rembe J, Thompson V, Stuermer E AIMS Microbiol. 2023; 8(4):372-387.

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Does the use of epicutaneous vacuum-assisted closure after revision surgery on the spine reduce further wound revision surgery?.

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Preoperative Octenidine Application in Breast Reconstruction Surgery.

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[Implementation of a thermal management concept to prevent perioperative hypothermia : Results of a 6‑month period in clinical practice].

Menzel M, Grote R, Leuchtmann D, Lautenschlager C, Roseler C, Brauer A Anaesthesist. 2016; 65(6):423-9.

PMID: 27188499 DOI: 10.1007/s00101-016-0158-3.

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