Two Ocular Infections During Conventional Chemotherapy in a Patient with Acute Lymphoblastic Leukemia: A Case Report

Overview

Journal Case Rep Oncol

Publisher Karger

Specialty Oncology

Date 2010 Aug 27

PMID 20740203

Citations 4

Authors

Ruba Taha

Ibrahim Al Hijji

Halima El Omri

Fareed Al-Laftah

Riham Negm

Mohammed Yassin

Hanadi El Ayoubi

Affiliations

Soon will be listed here.

Abstract

Viral retinitis due to cytomegalovirus (CMV) infection is rare in patients with acute leukemia who did not receive hematopoietic stem cell transplantation. We report a case of CMV retinitis that developed in a 49-year-old patient with acute lymphoblastic leukemia. The patient was treated with salvage chemotherapy using a hyper-CVAD regimen and did not receive hematopoietic stem cell transplantation. The incidence of CMV retinitis in this subgroup of patients is not described in literature. He had a very complicated course during chemotherapy but was successfully treated, with preservation of visual acuity, and to date he is in complete remission. Interestingly, prior to CMV retinitis, the patient had been diagnosed with and treated for candida retinitis. This case shows the importance of eye examination and care in patients diagnosed with hematological malignancies.

Citing Articles

Retinal and Preretinal Hemorrhages in a Patient Receiving Hyper-CVAD Chemotherapy for T-Cell Acute Lymphoblastic Leukemia.

Peddada K, Weiss S, Kumar S, Malik D Case Rep Ophthalmol Med. 2019; 2018:9457549.

PMID: 30627471 PMC: 6304476. DOI: 10.1155/2018/9457549.

An Interesting Case of CMV Retinitis in a Case of ALL on Maintenance Therapy.

Singh P, Dayama A, Maiwall R, Sehgal V, Venkatesh P, Mishra P Indian J Hematol Blood Transfus. 2014; 30(Suppl 1):154-8.

PMID: 25332566 PMC: 4192189. DOI: 10.1007/s12288-013-0305-9.

Cytomegalovirus Retinitis in an ALL Child during Maintenance Therapy Treated Successfully with Intravenous Ganciclovir.

Celiker H, Karaaslan A, Kepenekli Kadayifci E, Atici S, Soysal A, Kazokoglu H Case Rep Ophthalmol Med. 2014; 2014:294238.

PMID: 25161790 PMC: 4137609. DOI: 10.1155/2014/294238.

Outcome of cytomegalovirus retinitis in immunocompromised patients without Human Immunodeficiency Virus treated with intravitreal ganciclovir injection.

Agarwal A, Kumari N, Trehan A, Khadwal A, Dogra M, Gupta V Graefes Arch Clin Exp Ophthalmol. 2014; 252(9):1393-401.

PMID: 24557658 DOI: 10.1007/s00417-014-2587-5.

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