Relations Between Mucosal Immunity and Children's Mental Health: the Role of Child Sex

Overview

Journal Physiol Behav

Specialties Physiology
Psychiatry
Psychology
Social Sciences

Date 2010 Aug 25

PMID 20732336

Citations 19

Authors

Peggy S Keller

Mona El-Sheikh

Brian Vaughn

Douglas A Granger

Affiliations

Soon will be listed here.

Abstract

This study examines relations between children's salivary interleukin-6 (IL-6) and secretory immunoglobulin A (SIgA) and mental health. Child sex was considered as a moderator of relations. Data were from 329 normally developing children (M age=9.85years; SD=.98years); 67% of children were European American and 33% were African American. Saliva samples were obtained during the afternoon and assayed for SIgA and IL-6. Parents completed questionnaire measures of child internalizing and externalizing symptoms, and children completed self-report measures of anxiety and depression. Structural equation models were fit to the data, and indicated that greater levels of salivary IL-6 and SIgA were associated with adjustment problems more strongly for girls than for boys.

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