A Novel Degradable Polymeric Carrier for Selective Release and Imaging of Magnetic Nanoparticles

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2010 Aug 18

PMID 20714558

Citations 3

Authors

Dongyun Chen

Najun Li

Hongwei Gu

Xuewei Xia

Qingfeng Xu

Jianfeng Ge

Jianmei Lu

Yonggang Li

Affiliations

Soon will be listed here.

Abstract

A water-soluble, pH-responsive copolymer was synthesized successfully and used as a polymeric carrier to deliver hydrophobic paramagnetic nanoparticles into cells. In an acidic environment, the nanoparticles aggregate as the copolymer degrades, resulting in the enhancement of an in vitro MRI signal.

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