Anti-HCV Reactive Volunteer Blood Donors Distribution Character and Genotypes Switch in Xi'an, China

Overview

Journal Virol J

Publisher Biomed Central

Specialty Microbiology

Date 2010 Aug 12

PMID 20698949

Citations 4

Authors

Qiao-Hong Yue

Xian-Qing Zhang

Yu Shang

Yao-zhen Chen

Wen-Li Sun

Min-quan Su

Shi-Jie Mu

Xiao-Ke Hao

Xing-Bin Hu

Affiliations

Soon will be listed here.

Abstract

HCV is prevailed in the world as well as in China. Blood transfusion is one of the most common transmission pathways of this pathogen. Although data of HCV infection character were reported during the past years, anti-HCV reactive profile of China donors was not fully clear yet. Furthermore, infection progress was found related to the HCV genotype. Different genotype led to different efficacy when interferon was introduced into HCV therapy. Here we provided character data of HCV infection in China blood donors from the year of 2000 to 2009. The infection rate in local donors was lower than general population and descended from 0.80% to 0.40% or so in recent years. About 83% HCV strains were categorized into genotypes 1b and 2a. But 1b subtype cases climbed and 2a subtype cases decreased. The current study threw more light on HCV infection of blood donors in China, at least in the Northern region.

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