A Simplified Design of the Staggered Herringbone Micromixer for Practical Applications
Overview
Authors
Affiliations
We demonstrated a simple method for the device design of a staggered herringbone micromixer (SHM) using numerical simulation. By correlating the simulated concentrations with channel length, we obtained a series of concentration versus channel length profiles, and used mixing completion length L(m) as the only parameter to evaluate the performance of device structure on mixing. Fluorescence quenching experiments were subsequently conducted to verify the optimized SHM structure for a specific application. Good agreement was found between the optimization and the experimental data. Since L(m) is straightforward, easily defined and calculated parameter for characterization of mixing performance, this method for designing micromixers is simple and effective for practical applications.
In-line Raman imaging of mixing by herringbone grooves in microfluidic channels.
Klement W, Savino E, Browne W, Verpoorte E Lab Chip. 2024; 24(14):3498-3507.
PMID: 38920114 PMC: 11235414. DOI: 10.1039/d4lc00115j.
Herringbone micromixers for particle filtration.
Binsley J, Myers T, Pagliara S, Ogrin F Biomicrofluidics. 2023; 17(1):014106.
PMID: 36704613 PMC: 9873379. DOI: 10.1063/5.0134431.
Maged A, Abdelbaset R, Mahmoud A, Elkasabgy N Drug Deliv. 2022; 29(1):1549-1570.
PMID: 35612293 PMC: 9154770. DOI: 10.1080/10717544.2022.2069878.
A millisecond passive micromixer with low flow rate, low sample consumption and easy fabrication.
Liao Y, Mechulam Y, Lassalle-Kaiser B Sci Rep. 2021; 11(1):20119.
PMID: 34635693 PMC: 8505571. DOI: 10.1038/s41598-021-99471-x.
Hossain S, Tayeb N, Islam F, Kaseem M, Bui P, Bhuiya M Micromachines (Basel). 2021; 12(2).
PMID: 33669613 PMC: 7922677. DOI: 10.3390/mi12020211.