Longitudinally Extensive Transverse Myelitis Following Vaccination with Nasal Attenuated Novel Influenza A(H1N1) Vaccine

Overview

Journal Arch Neurol

Specialty Neurology

Date 2010 Aug 11

PMID 20697056

Citations 20

Authors

Wafa Akkad

Bassel Salem

Jerome W Freeman

Mark K Huntington

Affiliations

Soon will be listed here.

Abstract

Background: Transverse myelitis has been reported in association with vaccination, including influenza vaccination.

Objective: To describe a case of longitudinally extensive transverse myelitis associated with vaccination with a nasal attenuated novel influenza A(H1N1) vaccine.

Design: Case report.

Setting: Sanford University of South Dakota Hospital. Patient A 27-year-old woman with longitudinally extensive transverse myelitis.

Results: Four days following novel influenza A(H1N1) vaccination, the patient developed longitudinally extensive transverse myelitis. Extensive diagnostic evaluation effectively ruled out causes other than vaccination-associated transverse myelitis. Following treatment with corticosteroids and plasmapheresis, the patient made a significant recovery.

Conclusions: Transverse myelitis may be associated with vaccination against novel influenza A(H1N1). Additionally, we believe this to be the first report of longitudinally extensive transverse myelitis associated with any vaccine.

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A Case of Transverse Myelitis After Moderna Severe Acute Respiratory Syndrome Coronavirus Vaccination.

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