Temporal Variations Among Invasive Pneumococcal Disease Serotypes in Children and Adults in Germany (1992-2008)

Overview

Journal Int J Microbiol

Publisher Wiley

Specialty Microbiology

Date 2010 Jul 31

PMID 20671944

Citations 11

Authors

Matthias Imohl

Ralf Rene Reinert

Mark van der Linden

Affiliations

Soon will be listed here.

Abstract

Nationwide surveillance of invasive pneumococcal disease has been conducted in Germany since 1992. From 1992 to 2008, a total of 12,137 isolates from invasive pneumococcal disease were collected. Data on serotypes were available for 9,394 invasive isolates. The leading serotypes were serotypes 14 (16.5%), 3 (8.0%), 7F (7.6%), 1 (7.3%), and 23F (6.0%). Variations in serotype distribution over the years are particularly extensive, especially concerning serotype 14 (min 7.4%, max 33.5%) with the highest percentages among the isolates serotyped from around 1997 to 2006. Serotypes 1 and 7F increased over the last decade. No increase was observed concerning serotype 19A. Higher pneumococcal conjugate vaccine coverages were observed among children (7v, 57.3%; 10v, 72.8%; 13v, 83.5%) than among adults (7v, 39.9%; 10v, 55.5%; 13v, 73.5%). The temporal variations in serotype distribution have to be kept in mind when interpreting vaccine coverages reported in epidemiological studies.

Citing Articles

Serotype distribution and antimicrobial resistance of invasive Streptococcus pneumoniae isolates among Croatian adults during a fifteen-year period (2005-2019).

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Whole Genome Sequencing of 39 Invasive Streptococcus pneumoniae Sequence Type 199 Isolates Revealed Switches from Serotype 19A to 15B.

Makarewicz O, Lucas M, Brandt C, Herrmann L, Albersmeier A, Ruckert C PLoS One. 2017; 12(1):e0169370.

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Modeling the cost-effectiveness of infant vaccination with pneumococcal conjugate vaccines in Germany.

Kuhlmann A, von der Schulenburg J Eur J Health Econ. 2016; 18(3):273-292.

PMID: 26905404 DOI: 10.1007/s10198-016-0770-9.

Bacterial spectrum of spontaneously ruptured otitis media in the era of pneumococcal conjugate vaccination in Germany.

van der Linden M, Imohl M, Busse A, Rose M, Adam D Eur J Pediatr. 2014; 174(3):355-64.

PMID: 25169065 DOI: 10.1007/s00431-014-2409-0.

Penicillin susceptibility breakpoints for Streptococcus pneumoniae and their effect on susceptibility categorisation in Germany (1997-2013).

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