Central Fatigue: Issues Related to Cognition, Mood and Behavior, and Psychiatric Diagnoses

Overview

Journal PM R

Publisher Wiley

Specialties Emergency Medicine
Rehabilitation Medicine

Date 2010 Jul 27

PMID 20656614

Citations 37

Authors

Victoria M Leavitt

John DeLuca

Affiliations

Soon will be listed here.

Abstract

Describe and define the concept of central fatigue, as well as discuss the behavioral and neuroimaging studies that attempt its assessment and measurement. A brief description of how fatigue can be differentiated from psychiatric symptoms and from sleepiness is also provided. Promising directions for future research will be outlined in the final portion of this review. Despite its popular clinical use as a descriptor of certain symptomatology, fatigue is not a unitary construct. Describing central fatigue as distinct from peripheral fatigue represents one way of understanding the underlying neural and behavioral concomitants of fatigue.

Citing Articles

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Psychological responses to acute exercise in patients with stress-induced exhaustion disorder: a cross-over randomized trial.

Kling J, Persson Asplund R, Ekblom O, Blom V BMC Psychiatry. 2025; 25(1):72.

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Comparison of alterations in local field potentials and neuronal firing in mouse M1 and CA1 associated with central fatigue induced by high-intensity interval training and moderate-intensity continuous training.

Liu Y, Lao W, Mao H, Zhong Y, Wang J, Ouyang W Front Neurosci. 2024; 18:1428901.

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Are Surface Electromyography Parameters Indicative of Post-Activation Potentiation/Post-Activation Performance Enhancement, in Terms of Twitch Potentiation and Voluntary Performance? A Systematic Review.

Gallardo P, Giakas G, Sakkas G, Tsaklis P J Funct Morphol Kinesiol. 2024; 9(2).

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