MafB As a Type I Interferon Rheostat

Overview

Journal Nat Immunol

Date 2010 Jul 21

PMID 20644578

Citations 7

Authors

Hozumi Motohashi

Kazuhiko Igarashi

Affiliations

Soon will be listed here.

Citing Articles

MAFB shapes human monocyte-derived macrophage response to SARS-CoV-2 and controls severe COVID-19 biomarker expression.

Simon-Fuentes M, Rios I, Herrero C, Lasala F, Labiod N, Luczkowiak J JCI Insight. 2023; 8(24).

PMID: 37917179 PMC: 10807725. DOI: 10.1172/jci.insight.172862.

Myeloid-specific KDM6B inhibition sensitizes glioblastoma to PD1 blockade.

Goswami S, Raychaudhuri D, Singh P, Natarajan S, Chen Y, Poon C Nat Cancer. 2023; 4(10):1455-1473.

PMID: 37653141 DOI: 10.1038/s43018-023-00620-0.

MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity.

Vega M, Simon-Fuentes M, de la Aleja A, Nieto C, Colmenares M, Herrero C Front Immunol. 2020; 11:603507.

PMID: 33312178 PMC: 7708330. DOI: 10.3389/fimmu.2020.603507.

Transcription Factor MafB Suppresses Type I Interferon Production by CD14 Monocytes in Patients With Chronic Hepatitis C.

Liu T, Wang H, Zhang D, Zhu G Front Microbiol. 2019; 10:1814.

PMID: 31447817 PMC: 6692491. DOI: 10.3389/fmicb.2019.01814.

MafA Expression Preserves Immune Homeostasis in Human and Mouse Islets.

Singh T, Sarmiento L, Luan C, Prasad R, Johansson J, Cataldo L Genes (Basel). 2018; 9(12).

PMID: 30567413 PMC: 6315686. DOI: 10.3390/genes9120644.

References

Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y . Structural basis of alternative DNA recognition by Maf transcription factors. Mol Cell Biol. 2009; 29(23):6232-44. PMC: 2786689. DOI: 10.1128/MCB.00708-09. View

Kim H, Seed B . The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3. Nat Immunol. 2010; 11(8):743-50. PMC: 3050627. DOI: 10.1038/ni.1897. View

Nishimura W, Kondo T, Salameh T, El Khattabi I, Dodge R, Bonner-Weir S . A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol. 2006; 293(2):526-39. PMC: 2390934. DOI: 10.1016/j.ydbio.2006.02.028. View

Hober D, Sauter P . Pathogenesis of type 1 diabetes mellitus: interplay between enterovirus and host. Nat Rev Endocrinol. 2010; 6(5):279-89. DOI: 10.1038/nrendo.2010.27. View

Cooper J, Smyth D, Smiles A, Plagnol V, Walker N, Allen J . Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nat Genet. 2008; 40(12):1399-401. PMC: 2635556. DOI: 10.1038/ng.249. View