Structural Analysis of Lipopolysaccharides from Gram-negative Bacteria

Overview

Journal Biochemistry (Mosc)

Specialty Biochemistry

Date 2010 Jul 13

PMID 20618127

Citations 25

Authors

D S Kabanov

I R Prokhorenko

Affiliations

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Abstract

This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biological activities of lipopolysaccharides are presented. The structural homology of some oligosaccharide sequences of lipopolysaccharides to gangliosides of human cell membranes is considered.

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