Li R, Du Y, Zhou Y, Ouyang Z
Mol Biotechnol. 2024; .
PMID: 38940979
DOI: 10.1007/s12033-024-01232-4.
OConnor S, Le Bihan Y, Westwood I, Liu M, Mak O, Zazeri G
Molecules. 2022; 27(3).
PMID: 35164081
PMC: 8839746.
DOI: 10.3390/molecules27030817.
Hosfelt J, Richards A, Zheng M, Adura C, Nelson B, Yang A
Cell Chem Biol. 2021; 29(5):854-869.e9.
PMID: 34818532
PMC: 9124243.
DOI: 10.1016/j.chembiol.2021.11.004.
Skrzypczak N, Pyta K, Ruszkowski P, Mikolajczak P, Kucinska M, Murias M
J Enzyme Inhib Med Chem. 2021; 36(1):1898-1904.
PMID: 34344239
PMC: 8344233.
DOI: 10.1080/14756366.2021.1960829.
Terrab L, Wipf P
ACS Med Chem Lett. 2020; 11(3):232-236.
PMID: 32184949
PMC: 7073878.
DOI: 10.1021/acsmedchemlett.9b00583.
Medicinal chemistry strategies toward host targeting antiviral agents.
Ji X, Li Z
Med Res Rev. 2020; 40(5):1519-1557.
PMID: 32060956
PMC: 7228277.
DOI: 10.1002/med.21664.
The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity.
Echeverria P, Bhattacharya K, Joshi A, Wang T, Picard D
PLoS One. 2019; 14(2):e0208287.
PMID: 30726209
PMC: 6364869.
DOI: 10.1371/journal.pone.0208287.
Visualizing and Quantifying the Effect of the Inhibition of HSP70 on Breast Cancer Cells Based on Laser Scanning Microscopy.
Yu B, Yang H, Zhang X, Li H
Technol Cancer Res Treat. 2018; 17:1533033818785274.
PMID: 30175665
PMC: 6120176.
DOI: 10.1177/1533033818785274.
Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide.
Tamura T, Ueda T, Goto T, Tsukidate T, Shapira Y, Nishikawa Y
Nat Commun. 2018; 9(1):1870.
PMID: 29760386
PMC: 5951806.
DOI: 10.1038/s41467-018-04343-0.
Fluorescent-Linked Enzyme Chemoproteomic Strategy (FLECS) for Identifying HSP70 Inhibitors.
Haystead T
Methods Mol Biol. 2017; 1709:75-86.
PMID: 29177652
PMC: 6642669.
DOI: 10.1007/978-1-4939-7477-1_6.
Targeting secondary protein complexes in drug discovery: studying the druggability and chemical biology of the HSP70/BAG1 complex.
Evans L, Jones K, Cheeseman M
Chem Commun (Camb). 2017; 53(37):5167-5170.
PMID: 28439591
PMC: 5708526.
DOI: 10.1039/c7cc01376k.
An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine-56.
Pettinger J, Le Bihan Y, Widya M, van Montfort R, Jones K, Cheeseman M
Angew Chem Int Ed Engl. 2017; 56(13):3536-3540.
PMID: 28225177
PMC: 5412842.
DOI: 10.1002/anie.201611907.
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones A, Westwood I, Osborne J, Matthews T, Cheeseman M, Rowlands M
Sci Rep. 2016; 6:34701.
PMID: 27708405
PMC: 5052559.
DOI: 10.1038/srep34701.
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70.
Cheeseman M, Westwood I, Barbeau O, Rowlands M, Dobson S, Jones A
J Med Chem. 2016; 59(10):4625-36.
PMID: 27119979
PMC: 5371393.
DOI: 10.1021/acs.jmedchem.5b02001.
Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70).
Li X, Shao H, Taylor I, Gestwicki J
Curr Top Med Chem. 2016; 16(25):2729-40.
PMID: 27072701
PMC: 5502483.
DOI: 10.2174/1568026616666160413140911.
CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells.
Xu X, Bao Q, Jia J, Liu F, Guo X, Zhang M
Sci Rep. 2016; 6:19004.
PMID: 26743233
PMC: 4705544.
DOI: 10.1038/srep19004.
Hsp70 Isoforms Are Essential for the Formation of Kaposi's Sarcoma-Associated Herpesvirus Replication and Transcription Compartments.
Baquero-Perez B, Whitehouse A
PLoS Pathog. 2015; 11(11):e1005274.
PMID: 26587836
PMC: 4654589.
DOI: 10.1371/journal.ppat.1005274.
Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition.
Evans L, Cheeseman M, Yahya N, Jones K
PLoS One. 2015; 10(10):e0140006.
PMID: 26458144
PMC: 4601772.
DOI: 10.1371/journal.pone.0140006.
The Chemical Biology of Molecular Chaperones--Implications for Modulation of Proteostasis.
Brandvold K, Morimoto R
J Mol Biol. 2015; 427(18):2931-47.
PMID: 26003923
PMC: 4569545.
DOI: 10.1016/j.jmb.2015.05.010.
Blocking Hsp70 enhances the efficiency of amphotericin B treatment against resistant Aspergillus terreus strains.
Blatzer M, Blum G, Jukic E, Posch W, Gruber P, Nagl M
Antimicrob Agents Chemother. 2015; 59(7):3778-88.
PMID: 25870060
PMC: 4468683.
DOI: 10.1128/AAC.05164-14.
