Diagnostically Challenging Epithelial Odontogenic Tumors: a Selective Review of 7 Jawbone Lesions

Overview

Journal Head Neck Pathol

Specialties Oncology
Pathology

Date 2010 Jul 3

PMID 20596984

Citations 18

Authors

Fumio Ide

Kenji Mishima

Ichiro Saito

Kaoru Kusama

Affiliations

Soon will be listed here.

Abstract

Considerable variation in the clinicopathologic presentation of epithelial odontogenic tumors can sometimes be confusing and increase the chance of misdiagnosis. Seven diagnostically challenging jawbone lesions are described. There were 2 cases of mistaken identity in our ameloblastoma file. One unicystic type, initially diagnosed and treated as a lateral periodontal cyst, showed destructive recurrence 6 years postoperatively. The other globulomaxillary lesion was managed under the erroneous diagnosis of adenomatoid odontogenic tumor and recurred 4 times over an 11-year period. This tumor was found in retrospect to be consistent with an adenoid ameloblastoma with dentinoid. The diagnosis of cystic squamous odontogenic tumor (SOT) occurring as a radicular lesion of an impacted lower third molar was one of exclusion. Of two unsuspected keratocystic odontogenic tumors, one depicted deceptive features of pericoronitis, while the other case has long been in our files with the diagnosis of globulomaxillary SOT. Two cases of primary intraosseous squamous cell carcinoma appeared benign clinically and exhibited unexpected findings; an impacted third molar began to erupt in association with the growth of carcinoma and another periradicular carcinoma showed dentinoid formation. Cases selectively reviewed in this article present challenging problems which require clinical and radiographic correlation to avoid potential diagnostic pitfalls.

Citing Articles

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Primary intraosseous squamous cell carcinoma with pagetoid spread arising in periapical odontogenic epithelium of the maxilla.

Hashiguchi S, Kita R, Yoshino A, Koga K, Hasegawa H, Hamasaki M Med Mol Morphol. 2025; .

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Odontogenic carcinoma with dentinoid: case report and literature review of a rare entity.

Zeng M, Guo X, Chen X, Shao Z, Yang S BMC Oral Health. 2024; 24(1):704.

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Histopathological Insight of a Case of Adenoid Ameloblastoma: A Rare Odontogenic Tumor.

Keshwar S, Raut T, Jain N, Shrestha A, Jaisani M Case Rep Dent. 2024; 2024:8366045.

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A Systematic Review of Adenoid Ameloblastoma: A Newly Recognized Entity.

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