Restricted and Repetitive Behaviors in Toddlers and Preschoolers with Autism Spectrum Disorders Based on the Autism Diagnostic Observation Schedule (ADOS)

Overview

Journal Autism Res

Specialty Psychiatry

Date 2010 Jul 1

PMID 20589716

Citations 72

Authors

So Hyun Kim

Catherine Lord

Affiliations

Soon will be listed here.

Abstract

Restricted and repetitive behaviors (RRBs) observed during the Autism Diagnostic Observation Schedule [ADOS: Lord et al., 2000] were examined in a longitudinal data set of 455 toddlers and preschoolers (age 8-56 months) with clinical diagnosis of Autism Spectrum Disorders (ASD; autism, n=121 and pervasive developmental disorders-not otherwise specified (PDD-NOS), n=71), a nonspectrum disorder (NS; n=90), or typical development (TD; n=173). Even in the relatively brief semi-structured observations, GEE analyses of the severity and prevalence of RRBs differentiated children with ASD from those with NS and TD across all ages. RRB total scores on the ADOS were stable over time for children with ASD and NS; however, typically developing preschoolers showed lower RRB scores than typically developing toddlers. Nonverbal IQ (NVIQ) was more strongly related to the prevalence of RRBs in older children with PDD-NOS, NS, and TD than younger children under 2 years and those with autism. Item analyses revealed different relationships between individual items and NVIQ, age, diagnosis, and gender. These findings are discussed in terms of their implications for the etiology and treatment of RRBs as well as for the framework of ASD diagnostic criteria in future diagnostic systems.

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References

Howlin P, Goode S, Hutton J, Rutter M . Adult outcome for children with autism. J Child Psychol Psychiatry. 2004; 45(2):212-29. DOI: 10.1111/j.1469-7610.2004.00215.x. View

Cuccaro M, Shao Y, Grubber J, Slifer M, Wolpert C, Donnelly S . Factor analysis of restricted and repetitive behaviors in autism using the Autism Diagnostic Interview-R. Child Psychiatry Hum Dev. 2003; 34(1):3-17. DOI: 10.1023/a:1025321707947. View

Loh A, Soman T, Brian J, Bryson S, Roberts W, Szatmari P . Stereotyped motor behaviors associated with autism in high-risk infants: a pilot videotape analysis of a sibling sample. J Autism Dev Disord. 2007; 37(1):25-36. DOI: 10.1007/s10803-006-0333-5. View

Lord C, Risi S, Lambrecht L, Cook Jr E, Leventhal B, DiLavore P . The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism. J Autism Dev Disord. 2000; 30(3):205-23. View

Luyster R, Gotham K, Guthrie W, Coffing M, Petrak R, Pierce K . The Autism Diagnostic Observation Schedule-toddler module: a new module of a standardized diagnostic measure for autism spectrum disorders. J Autism Dev Disord. 2009; 39(9):1305-20. PMC: 2893552. DOI: 10.1007/s10803-009-0746-z. View

Lord C, Rutter M, Le Couteur A . Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord. 1994; 24(5):659-85. DOI: 10.1007/BF02172145. View

Szatmari P, Georgiades S, Bryson S, Zwaigenbaum L, Roberts W, Mahoney W . Investigating the structure of the restricted, repetitive behaviours and interests domain of autism. J Child Psychol Psychiatry. 2006; 47(6):582-90. DOI: 10.1111/j.1469-7610.2005.01537.x. View

Klin A, Pauls D, Schultz R, Volkmar F . Three diagnostic approaches to Asperger syndrome: implications for research. J Autism Dev Disord. 2005; 35(2):221-34. DOI: 10.1007/s10803-004-2001-y. View

Gotham K, Risi S, Pickles A, Lord C . The Autism Diagnostic Observation Schedule: revised algorithms for improved diagnostic validity. J Autism Dev Disord. 2006; 37(4):613-27. DOI: 10.1007/s10803-006-0280-1. View

10.

Morgan L, Wetherby A, Barber A . Repetitive and stereotyped movements in children with autism spectrum disorders late in the second year of life. J Child Psychol Psychiatry. 2008; 49(8):826-37. PMC: 2637361. DOI: 10.1111/j.1469-7610.2008.01904.x. View

11.

KANNER L . Autistic disturbances of affective contact. Acta Paedopsychiatr. 1968; 35(4):100-36. View

12.

Thelen E . Rhythmical stereotypies in normal human infants. Anim Behav. 1979; 27(Pt 3):699-715. DOI: 10.1016/0003-3472(79)90006-x. View

13.

Sallustro F, Atwell C . Body rocking, head banging, and head rolling in normal children. J Pediatr. 1978; 93(4):704-8. DOI: 10.1016/s0022-3476(78)80922-6. View

14.

Chawarska K, Klin A, Paul R, Volkmar F . Autism spectrum disorder in the second year: stability and change in syndrome expression. J Child Psychol Psychiatry. 2007; 48(2):128-38. DOI: 10.1111/j.1469-7610.2006.01685.x. View

15.

Ventola P, Kleinman J, Pandey J, Barton M, Allen S, Green J . Agreement among four diagnostic instruments for autism spectrum disorders in toddlers. J Autism Dev Disord. 2006; 36(7):839-47. DOI: 10.1007/s10803-006-0128-8. View

16.

Militerni R, Bravaccio C, Falco C, Fico C, Palermo M . Repetitive behaviors in autistic disorder. Eur Child Adolesc Psychiatry. 2002; 11(5):210-8. DOI: 10.1007/s00787-002-0279-x. View

17.

Richler J, Huerta M, Bishop S, Lord C . Developmental trajectories of restricted and repetitive behaviors and interests in children with autism spectrum disorders. Dev Psychopathol. 2010; 22(1):55-69. PMC: 2893549. DOI: 10.1017/S0954579409990265. View

18.

Bishop S, Richler J, Lord C . Association between restricted and repetitive behaviors and nonverbal IQ in children with autism spectrum disorders. Child Neuropsychol. 2006; 12(4-5):247-67. DOI: 10.1080/09297040600630288. View

19.

Evans D, Leckman J, Carter A, Reznick J, Henshaw D, King R . Ritual, habit, and perfectionism: the prevalence and development of compulsive-like behavior in normal young children. Child Dev. 1997; 68(1):58-68. View

20.

South M, Ozonoff S, McMahon W . Repetitive behavior profiles in Asperger syndrome and high-functioning autism. J Autism Dev Disord. 2005; 35(2):145-58. DOI: 10.1007/s10803-004-1992-8. View