» Articles » PMID: 20587083

Dirty Mouth? Should You Clean It Out? Decontamination for the Prevention of Pneumonia and Mortality in the ICU

Overview
Journal Crit Care
Specialty Critical Care
Date 2010 Jul 1
PMID 20587083
Citations 2
Authors
Affiliations
Soon will be listed here.
Citing Articles

Effects of prophylactic nebulized antibiotics on the prevention of ICU-acquired pneumonia: a systematic review and meta-analysis.

Gao M, Yu X, Liu X, Xu Y, Zhou H, Zhu Y PeerJ. 2024; 12:e18686.

PMID: 39686984 PMC: 11648687. DOI: 10.7717/peerj.18686.


Withholding selective decontamination of the digestive tract from critically ill patients must now surely be ethically questionable given the vast evidence base.

Zandstra D, Petros A, Taylor N, Silvestri L, de la Cal M, van Saene H Crit Care. 2010; 14(5):443.

PMID: 21067554 PMC: 3219259. DOI: 10.1186/cc9255.

References
1.
Lingnau W, Berger J, Javorsky F, Fille M, Allerberger F, BENZER H . Changing bacterial ecology during a five-year period of selective intestinal decontamination. J Hosp Infect. 1998; 39(3):195-206. DOI: 10.1016/s0195-6701(98)90258-4. View

2.
Oostdijk E, de Smet A, Blok H, Groen E, van Asselt G, Benus R . Ecological effects of selective decontamination on resistant gram-negative bacterial colonization. Am J Respir Crit Care Med. 2009; 181(5):452-7. DOI: 10.1164/rccm.200908-1210OC. View

3.
Verwaest C, Verhaegen J, Ferdinande P, Schetz M, Van den Berghe G, Verbist L . Randomized, controlled trial of selective digestive decontamination in 600 mechanically ventilated patients in a multidisciplinary intensive care unit. Crit Care Med. 1997; 25(1):63-71. DOI: 10.1097/00003246-199701000-00014. View

4.
Al-Tawfiq J, Abed M . Decreasing ventilator-associated pneumonia in adult intensive care units using the Institute for Healthcare Improvement bundle. Am J Infect Control. 2010; 38(7):552-6. DOI: 10.1016/j.ajic.2010.01.008. View

5.
Hammond J, Potgieter P, Saunders G, Forder A . Double-blind study of selective decontamination of the digestive tract in intensive care. Lancet. 1992; 340(8810):5-9. DOI: 10.1016/0140-6736(92)92422-c. View