Sensitized Two-photon Photochemical Deprotection

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2010 Jun 17

PMID 20552130

Citations 6

Authors

Michael C Pirrung

Timothy M Dore

Yue Zhu

Vipul S Rana

Affiliations

Soon will be listed here.

Abstract

The photoremovable protecting group NPPoc has little sensitivity to two-photon excitation, limiting its use in applications requiring high spatial control of its photochemistry. In the presence of a triplet sensitizer with a large two-photon absorption cross-section, however, the two-photon uncaging action cross-section is improved to levels useful in a variety of applications.

Citing Articles

Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions.

Barosi A, Dunkel P, Guenin E, Lalatonne Y, Zeitoun P, Fitton I RSC Adv. 2022; 10(6):3366-3370.

PMID: 35497736 PMC: 9048766. DOI: 10.1039/c9ra09828c.

Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Weinstain R, Slanina T, Kand D, Klan P Chem Rev. 2020; 120(24):13135-13272.

PMID: 33125209 PMC: 7833475. DOI: 10.1021/acs.chemrev.0c00663.

Two-photon sensitive protecting groups operating intramolecular electron transfer: uncaging of GABA and tryptophan.

Korzycka K, Bennett P, Cueto-Diaz E, Wicks G, Drobizhev M, Blanchard-Desce M Chem Sci. 2017; 6(4):2419-2426.

PMID: 28706657 PMC: 5488212. DOI: 10.1039/c4sc03775h.

From Monochrome to Technicolor: Simple Generic Approaches to Multicomponent Protein Nanopatterning Using Siloxanes with Photoremovable Protein-Resistant Protecting Groups.

El Zubir O, Xia S, Ducker R, Wang L, Mullin N, Cartron M Langmuir. 2017; 33(35):8829-8837.

PMID: 28551995 PMC: 5588097. DOI: 10.1021/acs.langmuir.7b01255.

A chemist and biologist talk to each other about caged neurotransmitters.

Ellis-Davies G Beilstein J Org Chem. 2013; 9:64-73.

PMID: 23399979 PMC: 3566830. DOI: 10.3762/bjoc.9.8.