[Intraoperative Parathyroid Hormone Determination for Primary Hyperparathyroidism]

Overview

Journal Chirurg

Specialty General Surgery

Date 2010 Jun 16

PMID 20549175

Citations 9

Authors

K Lorenz

H Dralle

Affiliations

Soon will be listed here.

Abstract

Intraoperative parathyroid hormone measurement (IOPTH) has proved to be an important promoter for focused and minimally invasive parathyroidectomy procedures in primary hyperparathyroidism. IOPTH enables multiglandular disease to be excluded with a high degree of certainty at the time of operation. The choice of the cut-off value for IOPTH as the criterion for success is of utmost importance with respect to the prognosis for operative success (biochemical healing). Advantages and disadvantages of the variety of existing IOPTH success criteria are confusing and their assessment is contradictory. Particularly with respect to cost-benefit aspects the standard application of IOPTH as "biochemical frozen section" even in conventional open parathyroidectomy remains a matter of controversy. This article gives an up-date on current knowledge and provides practical guidelines for clinical use of IOPTH.

Citing Articles

The value of intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidism and varying baseline parathyroid hormone levels.

Hargitai L, Bereuter C, Dunkler D, Geroldinger A, Scheuba C, Niederle B BJS Open. 2022; 6(6).

PMID: 36515670 PMC: 9749480. DOI: 10.1093/bjsopen/zrac118.

Questionable value of [Tc]-sestamibi scintigraphy in patients with pHPT and negative ultrasound.

Lenschow C, Wennmann A, Hendricks A, Germer C, Fassnacht M, Buck A Langenbecks Arch Surg. 2022; 407(8):3661-3669.

PMID: 35945299 PMC: 9722861. DOI: 10.1007/s00423-022-02648-9.

Applicability of a shortened interpretation model for intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidism in an endemic goiter region.

Riss P, Geroldinger A, Selberherr A, Brammen L, Heidtmann J, Scheuba C Eur Surg. 2018; 50(5):228-231.

PMID: 30294345 PMC: 6153981. DOI: 10.1007/s10353-018-0547-8.

[Diagnostics and treatment of primary hyperparathyroidism].

Nies C Chirurg. 2017; 88(12):1069-1080.

PMID: 28993832 DOI: 10.1007/s00104-017-0517-x.

[Pathology of parathyroid glands: Practical aspects for routine pathological investigations].

Sheu-Grabellus S, Schmid K Pathologe. 2015; 36(3):229-36.

PMID: 25898935 DOI: 10.1007/s00292-015-0016-0.

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