Neural Dynamics of in Vitro Cortical Networks Reflects Experienced Temporal Patterns

Overview

Journal Nat Neurosci

Date 2010 Jun 15

PMID 20543842

Citations 40

Authors

Hope A Johnson

Anubhuthi Goel

Dean V Buonomano

Affiliations

Soon will be listed here.

Abstract

Learning ultimately relies on changes in the flow of activity in neural microcircuits. The plasticity of neural dynamics is particularly relevant for the processing of temporal information. Chronic stimulation of cultured rat cortical networks revealed experience-dependent plasticity in neural dynamics. We observed changes in the temporal structure of activity that reflected the intervals used during training, suggesting that cortical circuits are inherently capable of temporal processing on short timescales.

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