» Articles » PMID: 20527889

Strategies at the Interface of Drug Discovery and Development: Early Optimization of the Solid State Phase and Preclinical Toxicology Formulation for Potential Drug Candidates

Overview
Journal J Med Chem
Specialty Chemistry
Date 2010 Jun 10
PMID 20527889
Citations 9
Authors
Affiliations
Soon will be listed here.
Citing Articles

Accelerated Development of Pharmaceuticals Past, Present, and Future.

Byrn S Pharm Res. 2024; 41(8):1547-1555.

PMID: 39107515 DOI: 10.1007/s11095-024-03737-8.


Exploring Taxifolin Polymorphs: Insights on Hydrate and Anhydrous Forms.

Stenger Moura F, Pinna N, Vivani R, Nunes G, Schoubben A, Bresolin T Pharmaceutics. 2021; 13(9).

PMID: 34575404 PMC: 8469002. DOI: 10.3390/pharmaceutics13091328.


Salts and Polymorph Screens for Bedaquiline.

Okezue M, Bogdanowich-Knipp S, Smith D, Zeller M, Byrn S, Smith P AAPS PharmSciTech. 2021; 22(7):228.

PMID: 34435280 PMC: 8387259. DOI: 10.1208/s12249-021-02106-7.


Molecular Simulation and Statistical Learning Methods toward Predicting Drug-Polymer Amorphous Solid Dispersion Miscibility, Stability, and Formulation Design.

Walden D, Bundey Y, Jagarapu A, Antontsev V, Chakravarty K, Varshney J Molecules. 2021; 26(1).

PMID: 33401494 PMC: 7794704. DOI: 10.3390/molecules26010182.


Co-crystals, Salts or Mixtures of Both? The Case of Tenofovir Alafenamide Fumarates.

Lengauer H, Makuc D, Sterk D, Perdih F, Pichler A, Trdan Lusin T Pharmaceutics. 2020; 12(4).

PMID: 32290280 PMC: 7238255. DOI: 10.3390/pharmaceutics12040342.