Preclinical Rheumatoid Arthritis: Identification, Evaluation, and Future Directions for Investigation

Overview

Journal Rheum Dis Clin North Am

Publisher Elsevier

Specialty Rheumatology

Date 2010 Jun 1

PMID 20510231

Citations 79

Authors

Kevin D Deane

Jill M Norris

V Michael Holers

Affiliations

Soon will be listed here.

Abstract

Rheumatoid arthritis (RA) likely develops in several phases, beginning with genetic risk, followed by asymptomatic autoimmunity, then finally, clinically apparent disease. Investigating the phases of disease that exist prior to the onset of symptoms (ie, the preclinical period of RA) will lead to understanding of the important relationships between genetic and environmental factors that may lead to disease, as well as allow for the development of predictive models for disease, and ultimately preventive strategies for RA.

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