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Total Intravenous Anesthesia with Propofol and Remifentanil in a Patient with MELAS Syndrome -A Case Report-

Overview
Journal Korean J Anesthesiol
Specialty Anesthesiology
Date 2010 May 29
PMID 20508802
Citations 5
Authors
Jin Suk Park
Chong Wha Baek
Hyun Kang
Su Man Cha
Jung Won Park
Yong Hun Jung
Young-Cheol Woo
Affiliations
Soon will be listed here.
Abstract

A 23-year-old woman with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) underwent a laparoscopy-assisted appendectomy. MELAS syndrome is a multisystemic disease caused by mitochondrial dysfunction. General anesthesia has several potential hazards to patients with MELAS syndrome, such as malignant hyperthermia, hypothermia, and metabolic acidosis. In this case, anesthesia was performed with propofol, remifentanil TCI, and atracurium without any surgical or anesthetic complications. We discuss the anesthetic effects of MELAS syndrome.

Citing Articles

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Successful Perioperative Management of Cochlear Implantation in a Patient With Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS).

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Dexmedetomidine as a non-triggering anesthetic agent in a patient with MELAS syndrome and systemic sepsis - A case report.

Kim S, Park S, Jung K Anesth Pain Med (Seoul). 2020; 14(4):416-422.

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A review of anaesthetic outcomes in patients with genetically confirmed mitochondrial disorders.

Smith A, Dunne E, Mannion M, OConnor C, Knerr I, Monavari A Eur J Pediatr. 2016; 176(1):83-88.

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[Characteristics of anesthesia in patients with MELAS syndrome: Case report of anesthesia in video-assisted thoracoscopy].

Haas A, Wappler F Anaesthesist. 2015; 64(10):747-53.

PMID: 26314741 DOI: 10.1007/s00101-015-0075-x.

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