» Articles » PMID: 20508235

Upper Extremity Function and Occupational Performance in Children with Spastic Cerebral Palsy Following Lower Extremity Botulinum Toxin Injections

Overview
Journal J Child Neurol
Specialties Neurology
Pediatrics
Date 2010 May 29
PMID 20508235
Citations 6
Authors
Affiliations
Soon will be listed here.
Abstract

We studied the effect of botulinum toxin A injections to the lower extremities of spastic cerebral palsy children on upper limb body function and occupational performance. A total of 16 children with spastic cerebral palsy, aged 2 to 8 years, Gross Motor Function Classification System levels I-IV, referred to a child neurology outpatient clinic for botulinum toxin A injections to the lower limbs, underwent 4 assessments: 1 month prior to injection, immediate pre injection, and at 1 and 5 to 6 months post injection. Three tools were used to test everyday function (Canadian Occupational Performance Measure and the Pediatric Evaluation of Disability Inventory) and upper extremity body function (Quality of Upper Extremity Skills Test). Significant improvement was documented between the immediate preinjection and the 2 postinjection assessments, indicating that improvement lasted for at least 6 months. Botulinum toxin A injections to the lower extremities in children with cerebral palsy improve upper limb body function and occupational performance.

Citing Articles

Benefits of the Global Integration Method (Método de Integração Global - MIG) in functional priorities of parents of Brazilian children and adolescents with autism spectrum disorder.

Nascimento A, Souto D, Cruz T, de Lima A, Oliveira G, Haase V BMC Pediatr. 2025; 25(1):75.

PMID: 39885464 PMC: 11781071. DOI: 10.1186/s12887-025-05422-0.


Update on Non-Interchangeability of Botulinum Neurotoxin Products.

Brin M, Nelson M, Ashourian N, Brideau-Andersen A, Maltman J Toxins (Basel). 2024; 16(6).

PMID: 38922160 PMC: 11209304. DOI: 10.3390/toxins16060266.


The impact of parent involvement on improving participation of children born preterm: The story in the baseline.

Killeen H, Anaby D Contemp Clin Trials Commun. 2022; 28:100942.

PMID: 35754976 PMC: 9218735. DOI: 10.1016/j.conctc.2022.100942.


A practical guide to optimizing the benefits of post-stroke spasticity interventions with botulinum toxin A: An international group consensus.

Francisco G, Balbert A, Bavikatte G, Bensmail D, Carda S, Deltombe T J Rehabil Med. 2020; 53(1):jrm00134.

PMID: 33057730 PMC: 8772370. DOI: 10.2340/16501977-2753.


Pharmacological differences and clinical implications of various botulinum toxin preparations: a critical appraisal.

Ferrari A, Manca M, Tugnoli V, Alberto L Funct Neurol. 2018; 33(1):7-18.

PMID: 29633692 PMC: 5901944. DOI: 10.11138/fneur/2018.33.1.007.