Analysis of Limb Function After Various Reconstruction Methods According to Tumor Location Following Resection of Pediatric Malignant Bone Tumors

Overview

Journal World J Surg Oncol

Publisher Biomed Central

Specialties General Surgery
Oncology

Date 2010 May 21

PMID 20482815

Citations 13

Authors

Yukihiro Yoshida

Shunzo Osaka

Yasuaki Tokuhashi

Affiliations

Soon will be listed here.

Abstract

Background: In the reconstruction of the affected limb in pediatric malignant bone tumors, since the loss of joint function affects limb-length discrepancy expected in the future, reconstruction methods that not only maximally preserve the joint function but also maintain good limb function are necessary. We analysis limb function of reconstruction methods by tumor location following resection of pediatric malignant bone tumors.

Patients And Methods: We classified the tumors according to their location into 3 types by preoperative MRI, and evaluated reconstruction methods after wide resection, paying attention to whether the joint function could be preserved. The mean age of the patients was 10.6 years, Osteosarcoma was observed in 26 patients, Ewing's sarcoma in 3, and PNET(primitive neuroectodermal tumor) and chondrosarcoma (grade 1) in 1 each.

Results: Type I were those located in the diaphysis, and reconstruction was performed using a vascularized fibular graft(vascularized fibular graft). Type 2 were those located in contact with the epiphyseal line or within 1 cm from this line, and VFG was performed in 1, and distraction osteogenesis in 1. Type III were those extending from the diaphysis to the epiphysis beyond the epiphyseal line, and a Growing Kotz was mainly used in 10 patients. The mean functional assessment score was the highest for Type I (96%: n = 4) according to the type and for VFG (99%) according to the reconstruction method.

Conclusion: The final functional results were the most satisfactory for Types I and II according to tumor location. Biological reconstruction such as VFG and distraction osteogenesis without a prosthesis are so high score in the MSTS rating system. Therefore, considering the function of the affected limb, a limb reconstruction method allowing the maximal preservation of joint function should be selected after careful evaluation of the effects of chemotherapy and the location of the tumor.

Citing Articles

Three-dimensional-printed porous prosthesis for the joint-sparing reconstruction of the proximal humeral tumorous defect.

Zhang Y, Lu M, Hu X, Li Z, Wang J, Gong T Front Bioeng Biotechnol. 2023; 10:1098973.

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Hip-preserving reconstruction of the proximal femur with a vascularized fibula autograft and liquid-nitrogen-treated tumor bearing bone.

Ayvaz M, Goker B, Leblebicioglu G Jt Dis Relat Surg. 2021; 32(3):792-797.

PMID: 34842116 PMC: 8650678. DOI: 10.52312/jdrs.2021.12.

Implementation of the three-dimensional printing technology in treatment of bone tumours: a case series.

Jovicic M, Vuletic F, Ribicic T, Simunic S, Petrovic T, Kolundzic R Int Orthop. 2020; 45(4):1079-1085.

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Outcomes of comprehensive treatment for primary osteosarcoma.

Hashimoto K, Nishimura S, Oka N, Akagi M SAGE Open Med. 2020; 8:2050312120923177.

PMID: 32547749 PMC: 7249600. DOI: 10.1177/2050312120923177.

Distraction osteogenesis reconstruction of large segmental bone defects after primary tumor resection: pitfalls and benefits.

Lesensky J, Prince D Eur J Orthop Surg Traumatol. 2017; 27(6):715-727.

PMID: 28643081 DOI: 10.1007/s00590-017-1998-5.

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