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Photoactive Molecules for Applications in Molecular Imaging and Cell Biology

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Journal Chem Soc Rev
Specialty Chemistry
Date 2010 May 19
PMID 20480074
Citations 29
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Abstract

Photoactive technology has proven successful for non-invasive regulation of biological activities and processes in living cells. With the light-directed generation of biomaterials or signals, mechanisms in cell biology can be investigated at the molecular level with spatial and temporal resolution. In this tutorial review, we aim to introduce the important applications of photoactive molecules for elucidating cell biology on aspects of protein engineering, fluorescence labelling, gene regulation and cell physiological functions.

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