Focus on Molecules: Heparanase

Overview

Journal Exp Eye Res

Specialty Ophthalmology

Date 2010 May 19

PMID 20478306

Citations 5

Authors

Yinghui Zhang

Denise S Ryan

Kraig S Bower

Neta Ilan

Israel Vlodavsky

Gordon W Laurie

Affiliations

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Citing Articles

Targeting Heparanase in Cancer: Inhibition by Synthetic, Chemically Modified, and Natural Compounds.

Mohan C, Hari S, Preetham H, Rangappa S, Barash U, Ilan N iScience. 2019; 15:360-390.

PMID: 31103854 PMC: 6548846. DOI: 10.1016/j.isci.2019.04.034.

Heparanase Overexpresses in Keratoconic Cornea and Tears Depending on the Pathologic Grade.

Garcia B, Garcia-Suarez O, Merayo-Lloves J, Ferrara G, Alcalde I, Gonzalez J Dis Markers. 2018; 2017:3502386.

PMID: 29379222 PMC: 5742882. DOI: 10.1155/2017/3502386.

Heparanase: From basic research to therapeutic applications in cancer and inflammation.

Vlodavsky I, Singh P, Boyango I, Gutter-Kapon L, Elkin M, Sanderson R Drug Resist Updat. 2016; 29:54-75.

PMID: 27912844 PMC: 5447241. DOI: 10.1016/j.drup.2016.10.001.

Heparanase expression correlates with poor survival in oral mucosal melanoma.

Wang X, Wen W, Wu H, Chen Y, Ren G, Guo W Med Oncol. 2013; 30(3):633.

PMID: 23794232 DOI: 10.1007/s12032-013-0633-5.

Molecular characterization, expression profiles, and association analysis with hematologic parameters of the porcine HPSE and HPSE2 genes.

Tao C, Wang W, Zhou P, Xia T, Zhou X, Zeng C J Appl Genet. 2012; 54(1):71-8.

PMID: 23109057 DOI: 10.1007/s13353-012-0119-8.

References

Berk R, Dong Z, Alousi S, Kosir M, Wang Y, Vlodavsky I . Murine ocular heparanase expression before and during infection with Pseudomonas aeruginosa. Invest Ophthalmol Vis Sci. 2004; 45(4):1182-7. DOI: 10.1167/iovs.03-0589. View

Ma P, Beck S, Raab R, McKown R, Coffman G, Utani A . Heparanase deglycanation of syndecan-1 is required for binding of the epithelial-restricted prosecretory mitogen lacritin. J Cell Biol. 2006; 174(7):1097-106. PMC: 1666580. DOI: 10.1083/jcb.200511134. View

Fux L, Ilan N, Sanderson R, Vlodavsky I . Heparanase: busy at the cell surface. Trends Biochem Sci. 2009; 34(10):511-9. PMC: 2755511. DOI: 10.1016/j.tibs.2009.06.005. View

Barash U, Cohen-Kaplan V, Arvatz G, Gingis-Velitski S, Levy-Adam F, Nativ O . A novel human heparanase splice variant, T5, endowed with protumorigenic characteristics. FASEB J. 2009; 24(4):1239-48. PMC: 2845434. DOI: 10.1096/fj.09-147074. View