Celiac Sprue: a Unique Autoimmune Disorder

Overview

Journal Expert Rev Clin Immunol

Specialty Allergy & Immunology

Date 2010 May 19

PMID 20477645

Citations 3

Authors

Shadi Rashtak

Eric V Marietta

Joseph A Murray

Affiliations

Soon will be listed here.

Abstract

Celiac sprue (CS) is a gluten-sensitive enteropathy with many autoimmune features. CS involves multiple organs through immune and nonimmune processes, and is frequently associated with other autoimmune disorders. This article reviews the co-occurrence of CS with autoimmune disorders of the cutaneous, nervous, endocrine, musculoskeletal, gastrointestinal and cardiovascular systems. The types of autoimmune disorders associated with CS and the prevalence of CS in other autoimmune disorders are also discussed. A brief review of the literature on the potential mechanisms behind these associations and the therapeutic effects of a gluten-free diet for autoimmune comorbidities in CS is also provided.

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