Muscle Power and Physical Activity Are Associated with Bone Strength in Older Men: The Osteoporotic Fractures in Men Study

Overview

Journal Bone

Specialties Endocrinology
Orthopedics

Date 2010 May 15

PMID 20466088

Citations 31

Authors

Julie M Cousins

Moira A Petit

Misti L Paudel

Brent C Taylor

Julie M Hughes

Jane A Cauley

Joseph M Zmuda

Peggy M Cawthon

Kristine E Ensrud

Affiliations

Soon will be listed here.

Abstract

The purpose of these analyses was to explore whether physical activity score, leg power or grip strength were associated with tibia and radius estimates of bone strength, cortical density, or total bone area. Peripheral quantitative computed tomography (pQCT) was used to compare tibial and radial bone volumetric density (vBMD, mg/cm(3)), total (ToA, mm(2)) and cortical (CoA, mm(2)) bone area, and estimates of bone compressive strength (bone strength index, BSI) and bending strength (polar strength strain index, SSIp) in a subset (n=1171) of men (> or = 65 years) who participated in the multi-site Osteoporotic Fractures in Men (MrOS) study. Physical activity was assessed by questionnaire (PASE), leg power by Nottingham Power Rig, and grip strength by a hand-held Dynamometer. Participants were categorized into quartiles of PASE, grip strength or leg power. The model was adjusted for age, race, clinic, weight, and limb length. In the tibia, BSI (+7%) and SSIp (+4%) were highest in the most active physically quartile compared to the least active (p<0.05). At the 4% site of the tibia, men with the greatest leg power had both greater ToA (+5%, p<0.001) and BSI (+5.3%, p=0.086) compared to men with the least leg power. At the 66% site of the tibia, the men with the highest leg power, compared to the men with the lowest leg power, had greater ToA (+3%, p=0.045) SSIp (+5%, p=0.008). Similar results were found at both the distal and midshaft of the radius. The findings of this study suggest the importance of maintaining levels of physical activity and muscle strength in older men to prevent bone fragility.

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References

Warner S, Shea J, Miller S, Shaw J . Adaptations in cortical and trabecular bone in response to mechanical loading with and without weight bearing. Calcif Tissue Int. 2006; 79(6):395-403. DOI: 10.1007/s00223-005-0293-3. View

Wang X, Kammerer C, Wheeler V, Patrick A, Bunker C, Zmuda J . Genetic and environmental determinants of volumetric and areal BMD in multi-generational families of African ancestry: the Tobago Family Health Study. J Bone Miner Res. 2007; 22(4):527-36. DOI: 10.1359/jbmr.070106. View

Bassey E, Fiatarone M, ONEILL E, Kelly M, Evans W, Lipsitz L . Leg extensor power and functional performance in very old men and women. Clin Sci (Lond). 1992; 82(3):321-7. DOI: 10.1042/cs0820321. View

Segal N, Torner J, Yang M, Curtis J, Felson D, Nevitt M . Muscle mass is more strongly related to hip bone mineral density than is quadriceps strength or lower activity level in adults over age 50 year. J Clin Densitom. 2008; 11(4):503-10. PMC: 2654209. DOI: 10.1016/j.jocd.2008.03.001. View

Ashe M, Liu-Ambrose T, Cooper D, Khan K, McKay H . Muscle power is related to tibial bone strength in older women. Osteoporos Int. 2008; 19(12):1725-32. DOI: 10.1007/s00198-008-0655-6. View

Sievanen H, Heinonen A, Kannus P . Adaptation of bone to altered loading environment: a biomechanical approach using X-ray absorptiometric data from the patella of a young woman. Bone. 1996; 19(1):55-9. DOI: 10.1016/8756-3282(96)00111-1. View

Ryan A, Treuth M, Rubin M, Miller J, Nicklas B, Landis D . Effects of strength training on bone mineral density: hormonal and bone turnover relationships. J Appl Physiol (1985). 1994; 77(4):1678-84. DOI: 10.1152/jappl.1994.77.4.1678. View

Burr D . Muscle strength, bone mass, and age-related bone loss. J Bone Miner Res. 1997; 12(10):1547-51. DOI: 10.1359/jbmr.1997.12.10.1547. View

Nguyen T, Center J, Eisman J . Osteoporosis in elderly men and women: effects of dietary calcium, physical activity, and body mass index. J Bone Miner Res. 2000; 15(2):322-31. DOI: 10.1359/jbmr.2000.15.2.322. View

10.

Burge R, Dawson-Hughes B, Solomon D, Wong J, King A, Tosteson A . Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2006; 22(3):465-75. DOI: 10.1359/jbmr.061113. View

11.

Jarvinen T, Kannus P, Sievanen H . Have the DXA-based exercise studies seriously underestimated the effects of mechanical loading on bone?. J Bone Miner Res. 1999; 14(9):1634-5. DOI: 10.1359/jbmr.1999.14.9.1634. View

12.

Harkonen R, Harju R, Alaranta H . Accuracy of the Jamar dynamometer. J Hand Ther. 1993; 6(4):259-62. DOI: 10.1016/s0894-1130(12)80326-7. View

13.

Bassey E, Short A . A new method for measuring power output in a single leg extension: feasibility, reliability and validity. Eur J Appl Physiol Occup Physiol. 1990; 60(5):385-90. DOI: 10.1007/BF00713504. View

14.

Frost H . Bone's mechanostat: a 2003 update. Anat Rec A Discov Mol Cell Evol Biol. 2003; 275(2):1081-101. DOI: 10.1002/ar.a.10119. View

15.

Hasegawa Y, Schneider P, Reiners C . Age, sex, and grip strength determine architectural bone parameters assessed by peripheral quantitative computed tomography (pQCT) at the human radius. J Biomech. 2001; 34(4):497-503. DOI: 10.1016/s0021-9290(00)00211-6. View

16.

Barry D, Kohrt W . BMD decreases over the course of a year in competitive male cyclists. J Bone Miner Res. 2007; 23(4):484-91. DOI: 10.1359/jbmr.071203. View

17.

Blank J, Cawthon P, Carrion-Petersen M, Harper L, Johnson J, Mitson E . Overview of recruitment for the osteoporotic fractures in men study (MrOS). Contemp Clin Trials. 2005; 26(5):557-68. DOI: 10.1016/j.cct.2005.05.005. View

18.

Devine A, Dhaliwal S, Dick I, Bollerslev J, Prince R . Physical activity and calcium consumption are important determinants of lower limb bone mass in older women. J Bone Miner Res. 2004; 19(10):1634-9. DOI: 10.1359/JBMR.040804. View

19.

Asikainen T, Kukkonen-Harjula K, Miilunpalo S . Exercise for health for early postmenopausal women: a systematic review of randomised controlled trials. Sports Med. 2004; 34(11):753-78. DOI: 10.2165/00007256-200434110-00004. View

20.

Aoyagi K, Ross P, Hayashi T, Okano K, Moji K, Sasayama H . Calcaneus bone mineral density is lower among men and women with lower physical performance. Calcif Tissue Int. 2000; 67(2):106-10. DOI: 10.1007/s00223001116. View