Bactericidal Effect of Iron Oxide Nanoparticles on Staphylococcus Aureus

Overview

Journal Int J Nanomedicine

Publisher Dove Medical Press

Specialty Biotechnology

Date 2010 May 14

PMID 20463943

Citations 85

Authors

Nhiem Tran

Aparna Mir

Dhriti Mallik

Arvind Sinha

Suprabha Nayar

Thomas J Webster

Affiliations

Soon will be listed here.

Abstract

In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at the highest concentration (3 mg/mL) at all time points.

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