Cyanogen Formation During Asymmetric Cyanohydrin Synthesis

Overview

Journal Chem Commun (Camb)

Publisher Royal Society of Chemistry

Specialty Chemistry

Date 2010 May 6

PMID 20442905

Citations 2

Authors

Victor Chechik

Marco Conte

Trevor Dransfield

Michael North

Marta Omedes-Pujol

Affiliations

Soon will be listed here.

Abstract

During asymmetric cyanohydrin synthesis catalysed by vanadium(V)oxo(salen) complexes, the catalysts are reduced to vanadium(IV)oxo(salen) as determined by EPR spectroscopy; the reducing agent is cyanide which is oxidised to cyanogen via a non-radical mechanism.

Citing Articles

Asymmetric Addition of Cyanide to β-Nitroalkenes Catalysed by Chiral Salen Complexes of Titanium(IV) and Vanadium(V).

North M, Watson J ChemCatChem. 2013; 5(8):2405-2409.

PMID: 24159364 PMC: 3798126. DOI: 10.1002/cctc.201300215.

Kinetics and mechanism of vanadium catalysed asymmetric cyanohydrin synthesis in propylene carbonate.

North M, Omedes-Pujol M Beilstein J Org Chem. 2010; 6:1043-55.

PMID: 21085513 PMC: 2982084. DOI: 10.3762/bjoc.6.119.