Soft Tissue Tumours: Imaging Strategy

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 2010 May 1

PMID 20432021

Citations 13

Authors

Herve J Brisse

Daniel Orbach

Jerzy Klijanienko

Affiliations

Soon will be listed here.

Abstract

Vascular tumours and malformations, fibrous and fibrohistiocytic tumours and pseudotumours are the most common benign soft-tissue masses observed in children, and can be treated conservatively. Rhabdomyosarcomas are the most frequent malignant tumours, accounting for about half of soft tissue sarcomas. A child referred for a soft-tissue mass should ideally be managed by a multidisciplinary team and primary excision should be proscribed until a definite diagnosis has been established. Clinical examination, conventional radiography and US with Doppler represent the first-line examinations and are sometimes sufficient to make a diagnosis. In all other situations, MRI is mandatory to establish the aggressiveness and extension of the tumour. This technique provides the relevant data to guide the decision regarding tissue sampling.

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References

Kransdorf M, Murphey M . Radiologic evaluation of soft-tissue masses: a current perspective. AJR Am J Roentgenol. 2000; 175(3):575-87. DOI: 10.2214/ajr.175.3.1750575. View

Brisse H, Orbach D, Klijanienko J, Freneaux P, Neuenschwander S . Imaging and diagnostic strategy of soft tissue tumors in children. Eur Radiol. 2006; 16(5):1147-64. DOI: 10.1007/s00330-005-0066-4. View

Imhof H, Czerny C, Hormann M, Krestan C . Tumors and tumor-like lesions of the neck: from childhood to adult. Eur Radiol. 2004; 14 Suppl 4:L155-65. DOI: 10.1007/s00330-003-2035-0. View

Eich G, Hoeffel J, Tschappeler H, Gassner I, Willi U . Fibrous tumours in children: imaging features of a heterogeneous group of disorders. Pediatr Radiol. 1998; 28(7):500-9. DOI: 10.1007/s002470050395. View

Bhargava R, Parham D, Lasater O, Chari R, Chen G, Fletcher B . MR imaging differentiation of benign and malignant peripheral nerve sheath tumors: use of the target sign. Pediatr Radiol. 1997; 27(2):124-9. DOI: 10.1007/s002470050082. View

Einarsdottir H, Karlsson M, Wejde J, Bauer H . Diffusion-weighted MRI of soft tissue tumours. Eur Radiol. 2004; 14(6):959-63. DOI: 10.1007/s00330-004-2237-0. View

Tung G, Davis L . The role of magnetic resonance imaging in the evaluation of the soft tissue mass. Crit Rev Diagn Imaging. 1993; 34(5):239-308. View

Ha T, Kleinman P, Fraire A, Spevak M, Nimkin K, Cohen I . MR imaging of benign fatty tumors in children: report of four cases and review of the literature. Skeletal Radiol. 1994; 23(5):361-7. DOI: 10.1007/BF02416994. View

Murphey M, Carroll J, Flemming D, Pope T, Gannon F, Kransdorf M . From the archives of the AFIP: benign musculoskeletal lipomatous lesions. Radiographics. 2004; 24(5):1433-66. DOI: 10.1148/rg.245045120. View

10.

Tateishi U, Gladish G, Kusumoto M, Hasegawa T, Yokoyama R, Tsuchiya R . Chest wall tumors: radiologic findings and pathologic correlation: part 1. Benign tumors. Radiographics. 2003; 23(6):1477-90. DOI: 10.1148/rg.236015526. View

11.

Beaman F, Kransdorf M, Andrews T, Murphey M, Arcara L, Keeling J . Superficial soft-tissue masses: analysis, diagnosis, and differential considerations. Radiographics. 2007; 27(2):509-23. DOI: 10.1148/rg.272065082. View

12.

De Schepper A, De Beuckeleer L, Vandevenne J, Somville J . Magnetic resonance imaging of soft tissue tumors. Eur Radiol. 2000; 10(2):213-23. DOI: 10.1007/s003300050037. View

13.

Ferrari A, Bisogno G, Macaluso A, Casanova M, DAngelo P, Pierani P . Soft-tissue sarcomas in children and adolescents with neurofibromatosis type 1. Cancer. 2007; 109(7):1406-12. DOI: 10.1002/cncr.22533. View

14.

Bodner G, Schocke M, Rachbauer F, Seppi K, Peer S, Fierlinger A . Differentiation of malignant and benign musculoskeletal tumors: combined color and power Doppler US and spectral wave analysis. Radiology. 2002; 223(2):410-6. DOI: 10.1148/radiol.2232010406. View

15.

Teo E, Strouse P, Hernandez R . MR imaging differentiation of soft-tissue hemangiomas from malignant soft-tissue masses. AJR Am J Roentgenol. 2000; 174(6):1623-8. DOI: 10.2214/ajr.174.6.1741623. View

16.

Verstraete K, Lang P . Bone and soft tissue tumors: the role of contrast agents for MR imaging. Eur J Radiol. 2000; 34(3):229-46. DOI: 10.1016/s0720-048x(00)00202-3. View

17.

Murphey M, Smith W, Smith S, Kransdorf M, Temple H . From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics. 1999; 19(5):1253-80. DOI: 10.1148/radiographics.19.5.g99se101253. View

18.

van Rijn R, Wilde J, Bras J, Oldenburger F, McHugh K, Merks J . Imaging findings in noncraniofacial childhood rhabdomyosarcoma. Pediatr Radiol. 2008; 38(6):617-34. PMC: 2367394. DOI: 10.1007/s00247-008-0751-y. View

19.

Laor T . MR imaging of soft tissue tumors and tumor-like lesions. Pediatr Radiol. 2003; 34(1):24-37. DOI: 10.1007/s00247-003-1086-3. View

20.

Toomayan G, Robertson F, Major N . Lower extremity compartmental anatomy: clinical relevance to radiologists. Skeletal Radiol. 2005; 34(6):307-13. DOI: 10.1007/s00256-005-0910-2. View