Inhibition of Adsorption of West-Nile and Herpes Simplex Viruses by Procaine

Overview

Journal Arch Virol

Specialty Microbiology

Date 1978 Jan 1

PMID 204270

Citations 3

Authors

P Fuchs

A Levanon

Affiliations

Soon will be listed here.

Abstract

The effect of the local anaesthetic drug procaine on the adsorption of two enveloped viruses was studied. Physiological concentrations of the drug (7 X 10(-3)--7 X 10(-2) M) strongly inhibited the adsorption of both West-Nile and herpes viruses as determined by plaque assay and the infective center assay.

Citing Articles

ProcCluster® and procaine hydrochloride inhibit the growth of species and exert antimicrobial properties during coinfection with influenza A viruses and .

Konig S, Schroeder J, Heinekamp T, Brakhage A, Loffler B, Engert B Front Cell Infect Microbiol. 2024; 14:1445428.

PMID: 39473925 PMC: 11518849. DOI: 10.3389/fcimb.2024.1445428.

ProcCluster and procaine hydrochloride inhibit the replication of influenza A virus .

Haring C, Schroeder J, Jungwirth J, Loffler B, Henke A, Engert B Front Microbiol. 2024; 15:1422651.

PMID: 39206370 PMC: 11350405. DOI: 10.3389/fmicb.2024.1422651.

The Local Anaesthetic Procaine Prodrugs ProcCluster and Procaine Hydrochloride Impair SARS-CoV-2 Replication and Egress In Vitro.

Haring C, Jungwirth J, Schroeder J, Loffler B, Engert B, Ehrhardt C Int J Mol Sci. 2023; 24(19).

PMID: 37834031 PMC: 10572566. DOI: 10.3390/ijms241914584.

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