Preeclampsia and Adiponectin in Cord Blood

Overview

Journal Horm Res Paediatr

Publisher Karger

Specialties Endocrinology
Pediatrics

Date 2010 Apr 17

PMID 20395665

Citations 2

Authors

Bjorn Ogland

Pal R Romundstad

Hege Vefring

Michele R Forman

Stein Tore Nilsen

Lars J Vatten

Affiliations

Soon will be listed here.

Abstract

Aims: To compare cord blood concentrations of total adiponectin in the offspring of pregnancies with and without preeclampsia.

Methods: Using a Luminex analyzer, cord blood adiponectin was measured in 182 singleton pregnancies with preeclampsia and compared to adiponectin measured in 511 singleton pregnancies without preeclampsia.

Results: Adiponectin levels in cord blood increased with increasing gestational age, but overall, crude levels were similar in pregnancies with and without preeclampsia. However, in pregnancies with early delivery (weeks 32-36), and in pregnancies with delivery after spontaneous contractions, adiponectin levels were higher in the preeclampsia group.

Conclusion: In preterm pregnancies and in pregnancies with spontaneous contractions, adiponectin levels in cord blood were higher in the preeclampsia group than in pregnancies without preeclampsia, maybe reflecting the need to optimize energy in preeclampsia.

Citing Articles

The influence of gestational hypertension on cord blood adiponectin levels: a case-controlled study.

Czubilinska-Lada J, Gliwinska A, Switochowska E, Nowak-Borzcka L, Sadownik B, Behrendt J Ther Adv Endocrinol Metab. 2022; 12:20420188211058582.

PMID: 35154636 PMC: 8832286. DOI: 10.1177/20420188211058582.

Maternal Preeclampsia and Androgens in the Offspring around Puberty: A Follow-Up Study.

Alsnes I, Janszky I, Asvold B, Inger Okland , Forman M, Vatten L PLoS One. 2016; 11(12):e0167714.

PMID: 27992610 PMC: 5167253. DOI: 10.1371/journal.pone.0167714.

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