Development of a Prediction Tool for Low Bone Mass Based on Clinical Data and Periapical Radiography

Overview

Journal Dentomaxillofac Radiol

Publisher Oxford University Press

Date 2010 Apr 17

PMID 20395463

Citations 7

Authors

R Licks

V Licks

F Ourique

H Radke Bittencourt

V Fontanella

Affiliations

Soon will be listed here.

Abstract

Objectives: This study aimed to develop and test a tool for low bone mass pre-screening by combining periapical radiographs with clinical risk factors.

Methods: The study sample consisted of 60 post-menopausal women over 40 years of age who were referred for dental radiographs. These patients also had their bone mineral density measured at the lumbar spine and proximal femur using dual-energy X-ray absorptiometry. Radiographic density measurements and 14 morphological features were obtained from each dental radiograph using digital image processing software. The clinical variables considered were age and bone mass index. Classification and regression tree analysis (CART) was used to test the predictive power of clinical and radiographic risk factors for classifying individuals.

Results: CART indicated that the most important variables for classifying patients were age, number of terminal points/periphery, periphery/trabecular area, radiographic density and bone mass index.

Conclusion: A combination of clinical and radiographic factors can be used to identify individuals with low bone mineral density, with higher accuracy than any one of these factors taken individually.

Citing Articles

The challenge of applying digital image processing software on intraoral radiographs for osteoporosis risk assessment.

Gullberg J, Al-Okshi A, Homar Asan D, Zainea A, Sundh D, Lorentzon M Dentomaxillofac Radiol. 2021; 51(1):20210175.

PMID: 34324394 PMC: 8693323. DOI: 10.1259/dmfr.20210175.

Changing trabecular patterns in panoramic radiographs of Swedish women during 25 years of follow-up.

Geraets W, Jonasson G, Hakeberg M Dentomaxillofac Radiol. 2020; 49(6):20190494.

PMID: 32207990 PMC: 7461738. DOI: 10.1259/dmfr.20190494.

Percentage fat fraction in magnetic resonance imaging: upgrading the osteoporosis-detecting parameter.

Chang R, Ma X, Jiang Y, Huang D, Chen X, Zhang M BMC Med Imaging. 2020; 20(1):30.

PMID: 32183731 PMC: 7079407. DOI: 10.1186/s12880-020-00423-0.

Evaluation of bone texture imaging parameters on panoramic radiographs of patients with Sheehan's syndrome: a STROBE-compliant case-control study.

de Sa Cavalcante D, da Silva Castro M, Quidute A, Martins M, Cid A, de Barros Silva P Osteoporos Int. 2019; 30(11):2257-2269.

PMID: 31372710 DOI: 10.1007/s00198-019-05086-4.

Effect of bisphosphonate treatment on the jawbone: an exploratory study using periapical and panoramic radiographic evaluation.

Barngkgei I, Halboub E, Almashraqi A Oral Radiol. 2018; 35(2):159-170.

PMID: 30484213 DOI: 10.1007/s11282-018-0358-4.

References

Taguchi A, Suei Y, Ohtsuka M, Otani K, Tanimoto K, Ohtaki M . Usefulness of panoramic radiography in the diagnosis of postmenopausal osteoporosis in women. Width and morphology of inferior cortex of the mandible. Dentomaxillofac Radiol. 1996; 25(5):263-7. DOI: 10.1259/dmfr.25.5.9161180. View

Lenchik L, Sartoris D . Current concepts in osteoporosis. AJR Am J Roentgenol. 1997; 168(4):905-11. DOI: 10.2214/ajr.168.4.9124138. View

Geraets W, van der Stelt P, Lips P, van Ginkel F . The radiographic trabecular pattern of hips in patients with hip fractures and in elderly control subjects. Bone. 1998; 22(2):165-73. DOI: 10.1016/s8756-3282(97)00233-0. View

Dargent-Molina P, Douchin M, Cormier C, Meunier P, Breart G . Use of clinical risk factors in elderly women with low bone mineral density to identify women at higher risk of hip fracture: The EPIDOS prospective study. Osteoporos Int. 2002; 13(7):593-9. DOI: 10.1007/s001980200078. View

Klemetti E, Kolmakov S, Kroger H . Pantomography in assessment of the osteoporosis risk group. Scand J Dent Res. 1994; 102(1):68-72. DOI: 10.1111/j.1600-0722.1994.tb01156.x. View

Korstjens C, Geraets W, van Ginkel F, Prahl-Andersen B, van der Stelt P, Burger E . Longitudinal analysis of radiographic trabecular pattern by image processing. Bone. 1995; 17(6):527-32. DOI: 10.1016/8756-3282(95)00403-3. View

Yasar F, Akgunlu F . The differences in panoramic mandibular indices and fractal dimension between patients with and without spinal osteoporosis. Dentomaxillofac Radiol. 2006; 35(1):1-9. DOI: 10.1259/dmfr/97652136. View

Horner K, Devlin H, Harvey L . Detecting patients with low skeletal bone mass. J Dent. 2002; 30(4):171-5. DOI: 10.1016/s0300-5712(02)00010-6. View

Black D, Steinbuch M, Palermo L, Dargent-Molina P, Lindsay R, Hoseyni M . An assessment tool for predicting fracture risk in postmenopausal women. Osteoporos Int. 2001; 12(7):519-28. DOI: 10.1007/s001980170072. View

10.

Klemetti E, Vainio P, Lassila V, Alhava E . Trabecular bone mineral density of mandible and alveolar height in postmenopausal women. Scand J Dent Res. 1993; 101(3):166-70. DOI: 10.1111/j.1600-0722.1993.tb01657.x. View

11.

Cummings S, Nevitt M, Browner W, Stone K, Fox K, Ensrud K . Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group. N Engl J Med. 1995; 332(12):767-73. DOI: 10.1056/NEJM199503233321202. View

12.

Dargent-Molina P, Piault S, Breart G . A triage strategy based on clinical risk factors for selecting elderly women for treatment or bone densitometry: the EPIDOS prospective study. Osteoporos Int. 2004; 16(8):898-906. DOI: 10.1007/s00198-004-1781-4. View

13.

Miliuniene E, Alekna V, Peciuliene V, Tamulaitiene M, Maneliene R . Relationship between mandibular cortical bone height and bone mineral density of lumbar spine. Stomatologija. 2008; 10(2):72-5. View

14.

Nackaerts O, Jacobs R, Devlin H, Pavitt S, Bleyen E, Yan B . Osteoporosis detection using intraoral densitometry. Dentomaxillofac Radiol. 2008; 37(5):282-7. DOI: 10.1259/dmfr/30424604. View

15.

Geraets W, Verheij J, van der Stelt P, Horner K, Lindh C, Nicopoulou-Karayianni K . Selecting regions of interest on intraoral radiographs for the prediction of bone mineral density. Dentomaxillofac Radiol. 2008; 37(7):375-9. DOI: 10.1259/dmfr/29966973. View

16.

Geraets W, van der Stelt P, Elders P . The radiographic trabecular bone pattern during menopause. Bone. 1993; 14(6):859-64. DOI: 10.1016/8756-3282(93)90315-2. View

17.

Sedrine W, Chevallier T, Zegels B, Kvasz A, Micheletti M, Gelas B . Development and assessment of the Osteoporosis Index of Risk (OSIRIS) to facilitate selection of women for bone densitometry. Gynecol Endocrinol. 2002; 16(3):245-50. View

18.

Ledgerton D, Horner K, Devlin H, Worthington H . Radiomorphometric indices of the mandible in a British female population. Dentomaxillofac Radiol. 2000; 28(3):173-81. DOI: 10.1038/sj/dmfr/4600435. View

19.

Geraets W, Verheij J, van der Stelt P, Horner K, Lindh C, Nicopoulou-Karayianni K . Prediction of bone mineral density with dental radiographs. Bone. 2007; 40(5):1217-21. DOI: 10.1016/j.bone.2007.01.009. View

20.

Geusens P, Hochberg M, van der Voort D, Pols H, van der Klift M, Siris E . Performance of risk indices for identifying low bone density in postmenopausal women. Mayo Clin Proc. 2002; 77(7):629-37. DOI: 10.4065/77.7.629. View