Oocyte Maturation Failure: a Syndrome of Bad Eggs

Overview

Journal Fertil Steril

Specialty Reproductive Medicine

Date 2010 Apr 10

PMID 20378111

Citations 46

Authors

Stephanie Beall

Carol Brenner

James Segars

Affiliations

Soon will be listed here.

Abstract

To show that disruption of meiotic competence results in cell cycle arrest, and the production of immature oocytes that are not capable of fertilization. Through an extensive review of animal studies and clinical case reports, we define the syndrome of oocyte maturation failure as a distinct oocyte disorder, present a classification system based on clinical parameters, and discuss the potential molecular origins for the disease.

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