» Articles » PMID: 20364534

Methylmercury Blood Guidance Values for Canada

Overview
Publisher Springer Nature
Specialty Public Health
Date 2010 Apr 7
PMID 20364534
Citations 27
Authors
Affiliations
Soon will be listed here.
Abstract

Exposure to methylmercury (MeHg) from fish and marine mammal consumption continues to present a public health concern. To date, developmental neurotoxicity is the most sensitive health outcome, forming the basis for health-risk assessments and the derivation of biomonitoring guidance values. This article summarizes existing Health Canada MeHg blood guidance values for general population and expands them to include a harmonized provisional interim blood guidance value of 8 microg/L based on the existing provisional Tolerable Daily Intake for children, pregnant women and women of childbearing age. Associated public health actions, according to age, sex, and level of exposure are recommended.

Citing Articles

Methodologies and challenges in Arctic human health risk assessment: case studies and evaluation of current practices.

Abass K, Dudarev A, Adlard B, Gillespie Z, Rautio A, Nych L Int J Circumpolar Health. 2024; 83(1):2428471.

PMID: 39563071 PMC: 11580145. DOI: 10.1080/22423982.2024.2428471.


Characterizing visual field loss from past mercury exposure in an Indigenous riverine community (Grassy Narrows First Nation, Canada): a cluster-based approach.

Philibert A, Tousignant B, Fillion M, Da Silva J, Mergler D Environ Health. 2024; 23(1):81.

PMID: 39375679 PMC: 11457346. DOI: 10.1186/s12940-024-01119-6.


Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations.

Wielsoe M, Long M, Sondergaard J, Bonefeld-Jorgensen E Int J Circumpolar Health. 2024; 83(1):2381308.

PMID: 39078885 PMC: 11290292. DOI: 10.1080/22423982.2024.2381308.


The evolution of symptoms of nervous system dysfunction in a First Nation community with a history of mercury exposure: a longitudinal study.

Philibert A, Da Silva J, Fillion M, Mergler D Environ Health. 2024; 23(1):50.

PMID: 38822381 PMC: 11140928. DOI: 10.1186/s12940-024-01089-9.


Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview.

Perini J, Cardoso J, Knesse A, Pessoa-Silva F, Vasconcellos A, Machado D Toxics. 2024; 12(3).

PMID: 38535959 PMC: 10975854. DOI: 10.3390/toxics12030226.


References
1.
Canuel R, de Grosbois S, Atikesse L, Lucotte M, Arp P, Ritchie C . New evidence on variations of human body burden of methylmercury from fish consumption. Environ Health Perspect. 2006; 114(2):302-6. PMC: 1367849. DOI: 10.1289/ehp.7857. View

2.
van Wijngaarden E, Beck C, Shamlaye C, Cernichiari E, Davidson P, Myers G . Benchmark concentrations for methyl mercury obtained from the 9-year follow-up of the Seychelles Child Development Study. Neurotoxicology. 2006; 27(5):702-9. DOI: 10.1016/j.neuro.2006.05.016. View

3.
KERSHAW T, Clarkson T, Dhahir P . The relationship between blood levels and dose of methylmercury in man. Arch Environ Health. 1980; 35(1):28-36. DOI: 10.1080/00039896.1980.10667458. View

4.
Innis S, Palaty J, Vaghri Z, Lockitch G . Increased levels of mercury associated with high fish intakes among children from Vancouver, Canada. J Pediatr. 2006; 148(6):759-63. DOI: 10.1016/j.jpeds.2006.02.001. View

5.
Budtz-Jorgensen E, Grandjean P, Keiding N, White R, Weihe P . Benchmark dose calculations of methylmercury-associated neurobehavioural deficits. Toxicol Lett. 2000; 112-113:193-9. DOI: 10.1016/s0378-4274(99)00283-0. View