A Novel Subclassification for Kunitz Proteinase Inhibitors from Leguminous Seeds

Overview

Journal Biochimie

Specialty Biochemistry

Date 2010 Apr 6

PMID 20363284

Citations 37

Authors

Maria Luiza V Oliva

Mariana C C Silva

Roberto C Sallai

Marlon V Brito

Misako U Sampaio

Affiliations

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Abstract

Kunitz-type trypsin inhibitors from legume seeds have been characterized structurally. The presence of Cys-Cys in single or double chains shows a new pattern of proteins structurally not so closely related to STI. Therefore, briefly, with regard to cysteine content, plant Kunitz proteinase inhibitors may be classified into four groups: no Cys-Cys at all, one, two and more than two Cys residues. Functional properties and diversity of these proteins are also briefly discussed.

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