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Snaclecs (snake C-type Lectins) That Inhibit or Activate Platelets by Binding to Receptors

Overview
Journal Toxicon
Specialty Toxicology
Date 2010 Mar 31
PMID 20350564
Citations 49
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Abstract

More than 300 known species of venomous snakes are classified into five families, Hydrophidae, Elapidae, Viperidae, Crotalidae and Colubidae. Venom proteins have also been demonstrated recently in other snakes and some lizards (Fry et al., 2006). Venom components that affect hemostasis are most generally found in Viperidae, and Crotalidae snakes but the others often contain some as well. This review concentrates on structural and functional properties of venom components of the C-type lectin related class (now named snaclecs) that inhibit or activate platelets by binding to receptors.

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