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Mechanisms Behind Estrogen's Beneficial Effect on Muscle Strength in Females

Overview
Specialty Orthopedics
Date 2010 Mar 26
PMID 20335737
Citations 63
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Abstract

Muscle weakness ensues when serum testosterone declines with age in men. Testosterone's female counterpart, estrogen, also has been implicated in age-related strength loss, but these results are less conclusive. Our working hypothesis is that estrogens do benefit muscle strength, and that the underlying mechanism involves estrogen receptors to improve muscle quality more so than quantity.

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