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Parity, Breastfeeding, and the Subsequent Risk of Maternal Type 2 Diabetes

Overview
Journal Diabetes Care
Specialty Endocrinology
Date 2010 Mar 25
PMID 20332359
Citations 27
Authors
Bette Liu
Louisa Jorm
Emily Banks
Affiliations
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Abstract

Objective: To examine the effect of childbearing and maternal breastfeeding on a woman's subsequent risk of developing type 2 diabetes.

Research Design And Methods: Using information on parity, breastfeeding, and diabetes collected from 52,731 women recruited into a cohort study, we estimated the risk of type 2 diabetes using multivariate logistic regression. RESULTS A total of 3,160 (6.0%) women were classified as having type 2 diabetes. Overall, nulliparous and parous women had a similar risk of diabetes. Among parous women, there was a 14% (95% CI 10-18%, P < 0.001) reduced likelihood of diabetes per year of breastfeeding. Compared to nulliparous women, parous women who did not breastfeed had a greater risk of diabetes (odds ratio 1.48, 95% CI 1.26-1.73, P < 0.001), whereas for women breastfeeding, the risk was not significantly increased.

Conclusions: Compared with nulliparous women, childbearing women who do not breastfeed have about a 50% increased risk of type 2 diabetes in later life. Breastfeeding substantially reduces this excess risk.

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