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Thermoregulation: Physiological and Clinical Considerations During Sedation and General Anesthesia

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Journal Anesth Prog
Date 2010 Mar 25
PMID 20331336
Citations 58
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Abstract

Mild hypothermia is common during deep sedation or general anesthesia and is frequently associated with patient discomfort and shivering. Greater declines in temperature can produce an even greater number of significant detrimental effects. This article reviews principles of thermoregulation and influences of anesthetic agents. An understanding of these will provide a foundation for strategies to reduce heat loss and better manage patient discomfort when it occurs.

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References
1.
Leslie K, Sessler D, Bjorksten A, Moayeri A . Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium. Anesth Analg. 1995; 80(5):1007-14. DOI: 10.1097/00000539-199505000-00027. View

2.
Michelson A, MacGregor H, Barnard M, Kestin A, Rohrer M, Valeri C . Reversible inhibition of human platelet activation by hypothermia in vivo and in vitro. Thromb Haemost. 1994; 71(5):633-40. View

3.
Schmied H, Kurz A, Sessler D, Kozek S, Reiter A . Mild hypothermia increases blood loss and transfusion requirements during total hip arthroplasty. Lancet. 1996; 347(8997):289-92. DOI: 10.1016/s0140-6736(96)90466-3. View

4.
Horn E, Sessler D, Standl T, Schroeder F, Bartz H, BEYER J . Non-thermoregulatory shivering in patients recovering from isoflurane or desflurane anesthesia. Anesthesiology. 1998; 89(4):878-86. DOI: 10.1097/00000542-199810000-00012. View

5.
Kurz A, Sessler D, Narzt E, Bekar A, Lenhardt R, Huemer G . Postoperative hemodynamic and thermoregulatory consequences of intraoperative core hypothermia. J Clin Anesth. 1995; 7(5):359-66. DOI: 10.1016/0952-8180(95)00028-g. View