Normal P300 Following Extensive Damage to the Left Medial Temporal Lobe

Overview

Journal J Neurol Neurosurg Psychiatry

Publisher BMJ Publishing Group

Specialties Neurology
Neurosurgery
Psychiatry

Date 1991 Mar 1

PMID 2030348

Citations 9

Authors

M D Rugg

C D Pickles

D D POTTER

R C Roberts

Affiliations

Soon will be listed here.

Abstract

Event-related potentials (ERPs) were recorded during auditory and visual "oddball" tasks from a patient with a severe verbal memory deficit due to a low grade infiltrating glioma which involved the full extent of the left medial temporal lobe. In both sensory modalities, the patient's oddball-evoked P300s were symmetrical and of normal amplitude. These findings are difficult to reconcile with the hypothesis that the hippocampus, or any other medial temporal structure, makes a substantial contribution to the scalp P300.

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