Primary Structure of Bovine Chromogranin B Deduced from CDNA Sequence

Overview

Journal Biochim Biophys Acta

Specialties Biochemistry
Biophysics

Date 1991 May 2

PMID 2025642

Citations 3

Authors

J W Bauer

R Fischer-Colbrie

Affiliations

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Abstract

The cDNA sequence of bovine chromogranin B has been determined. Bovine chromogranin B consists of 626 amino acids and contains 16 pairs of basic amino acids which might be used for generation of biological active peptides. A comparison of the amino acid sequences of chromogranin B from various species identifies regions of high homology at the N- and C-termini as well as stretches in the middle of the chromogranin B sequence.

Citing Articles

Processing of chromogranins in chromaffin cell culture: effects of reserpine and alpha-methyl-p-tyrosine.

Wolkersdorfer M, Laslop A, Lazure C, Fischer-Colbrie R, Winkler H Biochem J. 1996; 316 ( Pt 3):953-8.

PMID: 8670175 PMC: 1217441. DOI: 10.1042/bj3160953.

Novel peptides from adrenomedullary chromaffin vesicles.

Sigafoos J, Chestnut W, Merrill B, Taylor L, Diliberto Jr E, Viveros O J Anat. 1993; 183 ( Pt 2):253-64.

PMID: 8300415 PMC: 1259906.

The chromogranins A and B: the first 25 years and future perspectives.

Winkler H, Fischer-Colbrie R Neuroscience. 1992; 49(3):497-528.

PMID: 1501763 PMC: 7131462. DOI: 10.1016/0306-4522(92)90222-n.