Affinity-based Separations and Purifications. Patents and Literature

Overview

Journal Appl Biochem Biotechnol

Specialties Biochemistry
Biotechnology

Date 1991 Jan 1

PMID 2024980

Authors

J S Dordick

Affiliations

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Abstract

The separation and purification of biologically functional molecules (e.g., proteins, antibodies, peptides, hormones, low molecular weight biologicals) is of fundamental importance to biotechnology. Affinity separations have become a particularly attractive method for bioseparations due to their high degree of selectivity. Numerous affinity ligands have been prepared in recent years including lectins, nucleic acids, inhibitors, and immunoresponse agents. Furthermore, a variety of novel supports have been synthesized to aid in the development of commercially useful affinity separation systems. Recent US patents and scientific literature on affinity separations and purifications are surveyed. Patent abstracts are summarized individually and a list of literature references are given.

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