Modulation of Dendritic Cell Responses by Parasites: a Common Strategy to Survive

Overview

Journal J Biomed Biotechnol

Specialty Biology

Date 2010 Mar 6

PMID 20204070

Citations 25

Authors

Cesar A Terrazas

Luis I Terrazas

Lorena Gomez-Garcia

Affiliations

Soon will be listed here.

Abstract

Parasitic infections are one of the most important causes of morbidity and mortality in our planet and the immune responses triggered by these organisms are critical to determine their outcome. Dendritic cells are key elements for the development of immunity against parasites; they control the responses required to eliminate these pathogens while maintaining host homeostasis. However, there is evidence showing that parasites can influence and regulate dendritic cell function in order to promote a more permissive environment for their survival. In this review we will focus on the strategies protozoan and helminth parasites have developed to interfere with dendritic cell activities as well as in the possible mechanisms involved.

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