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Pathogenesis of Contact Lens-associated Microbial Keratitis

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Journal Optom Vis Sci
Date 2010 Mar 2
PMID 20190671
Citations 32
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Abstract

Sight-threatening microbial keratitis associated with contact lens wear remains a serious concern for patients, eye-care practitioners, and the contact lens industry. Several decades of research and some major advances in lens and solution technology have not resulted in a decline in disease incidence. Here, we offer a perspective on the complex pathogenesis of microbial keratitis, the factors that have prevented a better understanding of this disease, and new approaches being used to tackle this important clinical problem.

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